prfC protein (Acidovorax citrulli) - STRING interaction network

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prfC

Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (542 aa)

Predicted Functional Partners:

rpmA

0.891

rpmG

0.848

rplS

0.826

rplT

0.822

rplL

0.804

rpmF

0.795

rplI

0.795

rplQ

0.794

rplM

0.787

rplK

0.783

Your Current Organism:

Acidovorax citrulli

NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
prfC	rplI	Aave_4062	Aave_1231	Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	LSU ribosomal protein L9P; Binds to the 23S rRNA.	0.795
prfC	rplK	Aave_4062	Aave_4535	Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.783
prfC	rplL	Aave_4062	Aave_4532	Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	LSU ribosomal protein L12P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.	0.804
prfC	rplM	Aave_4062	Aave_4053	Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.787
prfC	rplQ	Aave_4062	Aave_0627	Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	PFAM: ribosomal protein L17; KEGG: rfr:Rfer_4216 ribosomal protein L17.	0.794
prfC	rplS	Aave_4062	Aave_1887	Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.826
prfC	rplT	Aave_4062	Aave_2856	Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.822
prfC	rpmA	Aave_4062	Aave_3674	Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	PFAM: ribosomal protein L27; KEGG: pol:Bpro_0838 ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.	0.891
prfC	rpmF	Aave_4062	Aave_1181	Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	TIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; KEGG: rfr:Rfer_1728 ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.	0.795
prfC	rpmG	Aave_4062	Aave_3429	Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	PFAM: ribosomal protein L33; KEGG: rfr:Rfer_3181 ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.	0.848
rplI	prfC	Aave_1231	Aave_4062	LSU ribosomal protein L9P; Binds to the 23S rRNA.	Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	0.795
rplI	rplK	Aave_1231	Aave_4535	LSU ribosomal protein L9P; Binds to the 23S rRNA.	LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.990
rplI	rplL	Aave_1231	Aave_4532	LSU ribosomal protein L9P; Binds to the 23S rRNA.	LSU ribosomal protein L12P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.	0.994
rplI	rplM	Aave_1231	Aave_4053	LSU ribosomal protein L9P; Binds to the 23S rRNA.	LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.990
rplI	rplQ	Aave_1231	Aave_0627	LSU ribosomal protein L9P; Binds to the 23S rRNA.	PFAM: ribosomal protein L17; KEGG: rfr:Rfer_4216 ribosomal protein L17.	0.993
rplI	rplS	Aave_1231	Aave_1887	LSU ribosomal protein L9P; Binds to the 23S rRNA.	LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.994
rplI	rplT	Aave_1231	Aave_2856	LSU ribosomal protein L9P; Binds to the 23S rRNA.	LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.994
rplI	rpmA	Aave_1231	Aave_3674	LSU ribosomal protein L9P; Binds to the 23S rRNA.	PFAM: ribosomal protein L27; KEGG: pol:Bpro_0838 ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.	0.989
rplI	rpmF	Aave_1231	Aave_1181	LSU ribosomal protein L9P; Binds to the 23S rRNA.	TIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; KEGG: rfr:Rfer_1728 ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.	0.980
rplI	rpmG	Aave_1231	Aave_3429	LSU ribosomal protein L9P; Binds to the 23S rRNA.	PFAM: ribosomal protein L33; KEGG: rfr:Rfer_3181 ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.	0.988

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