node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aave_1588 | Aave_3585 | Aave_1588 | Aave_3585 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.920 |
Aave_1588 | dtd | Aave_1588 | Aave_4243 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.422 |
Aave_3585 | Aave_1588 | Aave_3585 | Aave_1588 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.920 |
Aave_3585 | dtd | Aave_3585 | Aave_4243 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.422 |
Aave_4244 | Aave_4245 | Aave_4244 | Aave_4245 | TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: pol:Bpro_4099 cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | PFAM: helicase domain protein; DbpA, RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: pol:Bpro_0650 DEAD/DEAH box helicase-like; Belongs to the DEAD box helicase family. | 0.643 |
Aave_4244 | Aave_4247 | Aave_4244 | Aave_4247 | TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: pol:Bpro_4099 cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: bxe:Bxe_B2036 putative diguanylate cyclase (GGDEF domain). | 0.407 |
Aave_4244 | amn | Aave_4244 | Aave_4246 | TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: pol:Bpro_4099 cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | 0.556 |
Aave_4244 | dtd | Aave_4244 | Aave_4243 | TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: pol:Bpro_4099 cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.841 |
Aave_4245 | Aave_4244 | Aave_4245 | Aave_4244 | PFAM: helicase domain protein; DbpA, RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: pol:Bpro_0650 DEAD/DEAH box helicase-like; Belongs to the DEAD box helicase family. | TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: pol:Bpro_4099 cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | 0.643 |
Aave_4245 | Aave_4247 | Aave_4245 | Aave_4247 | PFAM: helicase domain protein; DbpA, RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: pol:Bpro_0650 DEAD/DEAH box helicase-like; Belongs to the DEAD box helicase family. | TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: bxe:Bxe_B2036 putative diguanylate cyclase (GGDEF domain). | 0.482 |
Aave_4245 | amn | Aave_4245 | Aave_4246 | PFAM: helicase domain protein; DbpA, RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: pol:Bpro_0650 DEAD/DEAH box helicase-like; Belongs to the DEAD box helicase family. | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | 0.561 |
Aave_4245 | dtd | Aave_4245 | Aave_4243 | PFAM: helicase domain protein; DbpA, RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: pol:Bpro_0650 DEAD/DEAH box helicase-like; Belongs to the DEAD box helicase family. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.682 |
Aave_4247 | Aave_4244 | Aave_4247 | Aave_4244 | TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: bxe:Bxe_B2036 putative diguanylate cyclase (GGDEF domain). | TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: pol:Bpro_4099 cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | 0.407 |
Aave_4247 | Aave_4245 | Aave_4247 | Aave_4245 | TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: bxe:Bxe_B2036 putative diguanylate cyclase (GGDEF domain). | PFAM: helicase domain protein; DbpA, RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: pol:Bpro_0650 DEAD/DEAH box helicase-like; Belongs to the DEAD box helicase family. | 0.482 |
Aave_4247 | amn | Aave_4247 | Aave_4246 | TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: bxe:Bxe_B2036 putative diguanylate cyclase (GGDEF domain). | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | 0.675 |
Aave_4247 | dtd | Aave_4247 | Aave_4243 | TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: bxe:Bxe_B2036 putative diguanylate cyclase (GGDEF domain). | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.407 |
amn | Aave_4244 | Aave_4246 | Aave_4244 | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: pol:Bpro_4099 cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. | 0.556 |
amn | Aave_4245 | Aave_4246 | Aave_4245 | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | PFAM: helicase domain protein; DbpA, RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: pol:Bpro_0650 DEAD/DEAH box helicase-like; Belongs to the DEAD box helicase family. | 0.561 |
amn | Aave_4247 | Aave_4246 | Aave_4247 | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: bxe:Bxe_B2036 putative diguanylate cyclase (GGDEF domain). | 0.675 |
amn | dtd | Aave_4246 | Aave_4243 | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. | 0.480 |