Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Aave_4349hydroxymethylglutaryl-CoA lyase; PFAM: pyruvate carboxyltransferase; KEGG: rfr:Rfer_3824 pyruvate carboxyltransferase. (303 aa)    
Predicted Functional Partners:
Aave_4353
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: rfr:Rfer_3831 enoyl-CoA hydratase/isomerase.
 
 0.996
Aave_3127
KEGG: pol:Bpro_1905 3-oxoacid CoA-transferase, subunit A; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase.
  
 
 0.933
Aave_3126
KEGG: pol:Bpro_1906 3-oxoacid CoA-transferase, subunit B; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase.
  
 
 0.930
Aave_0119
TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; KEGG: pol:Bpro_0120 acetoacetyl-CoA synthase.
 
 
 0.929
Aave_0031
acetyl-CoA acetyltransferase; KEGG: eba:p2A409 beta-ketothiolase protein; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.926
Aave_2478
KEGG: pol:Bpro_2140 acetyl-CoA C-acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.926
Aave_2879
KEGG: pol:Bpro_2572 acetyl-CoA C-acyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.926
Aave_4085
KEGG: pol:Bpro_3953 acetyl-CoA C-acyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; 3-oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.926
Aave_4368
KEGG: pol:Bpro_4187 acetyl-CoA C-acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.926
Aave_1586
TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: rfr:Rfer_2069 3-hydroxybutyrate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.914
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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