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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Aave_4366PFAM: acyltransferase 3; KEGG: mxa:MXAN_1041 acyltransferase family protein. (386 aa)    
Predicted Functional Partners:
Aave_4367
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pol:Bpro_4186 short-chain dehydrogenase/reductase SDR.
       0.777
Aave_4368
KEGG: pol:Bpro_4187 acetyl-CoA C-acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
       0.773
Aave_4365
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: rfr:Rfer_3838 acyl-CoA dehydrogenase-like.
       0.581
aceK
Isocitrate dehydrogenase kinasephosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
       0.553
Aave_4142
PFAM: glycosyl transferase, family 2; Methionine biosynthesis MetW; Methyltransferase type 11; Methyltransferase type 12; KEGG: rru:Rru_B0044 glycosyl transferase, family 2.
  
  
 0.488
Aave_4370
Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
       0.463
Aave_4371
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: pol:Bpro_4190 acyl-CoA dehydrogenase-like.
       0.416
Aave_3389
KEGG: psb:Psyr_3815 hypothetical protein.
  
     0.412
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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