Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cheDCheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family. (253 aa)    
Predicted Functional Partners:
Aave_2113
KEGG: tbd:Tbd_2406 chemotaxis sensory transducer; TIGRFAM: PAS sensor protein; PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAC repeat-containing protein.
 
 
 0.979
cheB-2
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
  
 0.974
Aave_4376
MCP methyltransferase, CheR-type; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
  
 0.965
Aave_4378
CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region, ATPase domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: rfr:Rfer_0567 CheA signal transduction histidine kinase.
 
  
 0.961
Aave_3516
KEGG: dar:Daro_3102 hypothetical protein.
  
 
 0.956
Aave_2417
Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
  
 0.953
Aave_4377
PFAM: CheW domain protein; KEGG: rfr:Rfer_0568 CheW protein.
 
  
 0.931
Aave_0168
PFAM: chemotaxis sensory transducer; KEGG: reu:Reut_B3725 chemotaxis sensory transducer.
 
 0.924
Aave_1344
PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: rfr:Rfer_2507 methyl-accepting chemotaxis sensory transducer.
 
  0.920
Aave_0035
PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: rfr:Rfer_2354 methyl-accepting chemotaxis sensory transducer.
 
  0.919
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.