Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Aave_4397KEGG: rfr:Rfer_0634 flagellar protein FliT. (99 aa)    
Predicted Functional Partners:
Aave_4398
PFAM: flagellar protein FliS; KEGG: rfr:Rfer_0633 flagellar protein FliS.
  
  
 0.989
Aave_4399
Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
 
 0.957
Aave_4431
TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; KEGG: rfr:Rfer_3724 flagellin-like.
 
 
 0.841
Aave_4430
TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: rfr:Rfer_3723 flagellar hook-associated protein; Belongs to the flagella basal body rod proteins family.
  
  
 0.824
flhD
Flagellar transcriptional activator, FlhD subunit; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.
 
   
 0.810
flhC
Flagellar transcriptional activator, FlhC subunit; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family.
 
   
 0.768
Aave_4051
KEGG: pol:Bpro_4111 hypothetical protein.
  
     0.744
Aave_0065
KEGG: rfr:Rfer_0054 methyltransferase type 12.
  
     0.733
Aave_4386
PFAM: flagellar biosynthesis protein, FliO; KEGG: rfr:Rfer_0559 hypothetical protein.
  
  
 0.730
fliE
TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; KEGG: rfr:Rfer_0549 flagellar hook-basal body complex protein.
 
  
 0.674
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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