| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Aave_2417 | Aave_4378 | Aave_2417 | Aave_4378 | Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region, ATPase domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: rfr:Rfer_0567 CheA signal transduction histidine kinase. | 0.998 |
| Aave_2417 | Aave_4388 | Aave_2417 | Aave_4388 | Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; KEGG: rfr:Rfer_0557 flagellar motor switch protein FliM. | 0.958 |
| Aave_2417 | Aave_4395 | Aave_2417 | Aave_4395 | Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family. | 0.762 |
| Aave_2417 | Aave_4398 | Aave_2417 | Aave_4398 | Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | PFAM: flagellar protein FliS; KEGG: rfr:Rfer_0633 flagellar protein FliS. | 0.958 |
| Aave_2417 | Aave_4408 | Aave_2417 | Aave_4408 | Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | KEGG: rfr:Rfer_3702 MotA/TolQ/ExbB proton channel. | 0.959 |
| Aave_2417 | Aave_4409 | Aave_2417 | Aave_4409 | Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | PFAM: OmpA/MotB domain protein; KEGG: rfr:Rfer_3703 OmpA/MotB. | 0.921 |
| Aave_2417 | Aave_4411 | Aave_2417 | Aave_4411 | Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | Chemotaxis phosphatase, CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). | 0.969 |
| Aave_2417 | Aave_4422 | Aave_2417 | Aave_4422 | Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein. | 0.840 |
| Aave_2417 | Aave_4430 | Aave_2417 | Aave_4430 | Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: rfr:Rfer_3723 flagellar hook-associated protein; Belongs to the flagella basal body rod proteins family. | 0.963 |
| Aave_2417 | fliA | Aave_2417 | Aave_4416 | Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | RNA polymerase, sigma 28 subunit, SigD/FliA/WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. | 0.936 |
| Aave_4378 | Aave_2417 | Aave_4378 | Aave_2417 | CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region, ATPase domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: rfr:Rfer_0567 CheA signal transduction histidine kinase. | Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | 0.998 |
| Aave_4378 | Aave_4388 | Aave_4378 | Aave_4388 | CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region, ATPase domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: rfr:Rfer_0567 CheA signal transduction histidine kinase. | PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; KEGG: rfr:Rfer_0557 flagellar motor switch protein FliM. | 0.851 |
| Aave_4378 | Aave_4395 | Aave_4378 | Aave_4395 | CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region, ATPase domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: rfr:Rfer_0567 CheA signal transduction histidine kinase. | Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family. | 0.654 |
| Aave_4378 | Aave_4398 | Aave_4378 | Aave_4398 | CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region, ATPase domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: rfr:Rfer_0567 CheA signal transduction histidine kinase. | PFAM: flagellar protein FliS; KEGG: rfr:Rfer_0633 flagellar protein FliS. | 0.837 |
| Aave_4378 | Aave_4408 | Aave_4378 | Aave_4408 | CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region, ATPase domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: rfr:Rfer_0567 CheA signal transduction histidine kinase. | KEGG: rfr:Rfer_3702 MotA/TolQ/ExbB proton channel. | 0.916 |
| Aave_4378 | Aave_4409 | Aave_4378 | Aave_4409 | CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region, ATPase domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: rfr:Rfer_0567 CheA signal transduction histidine kinase. | PFAM: OmpA/MotB domain protein; KEGG: rfr:Rfer_3703 OmpA/MotB. | 0.952 |
| Aave_4378 | Aave_4411 | Aave_4378 | Aave_4411 | CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region, ATPase domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: rfr:Rfer_0567 CheA signal transduction histidine kinase. | Chemotaxis phosphatase, CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). | 0.987 |
| Aave_4378 | Aave_4422 | Aave_4378 | Aave_4422 | CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region, ATPase domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: rfr:Rfer_0567 CheA signal transduction histidine kinase. | Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein. | 0.720 |
| Aave_4378 | Aave_4430 | Aave_4378 | Aave_4430 | CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region, ATPase domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: rfr:Rfer_0567 CheA signal transduction histidine kinase. | TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: rfr:Rfer_3723 flagellar hook-associated protein; Belongs to the flagella basal body rod proteins family. | 0.714 |
| Aave_4378 | fliA | Aave_4378 | Aave_4416 | CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region, ATPase domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: rfr:Rfer_0567 CheA signal transduction histidine kinase. | RNA polymerase, sigma 28 subunit, SigD/FliA/WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. | 0.619 |