node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aave_1306 | Aave_4564 | Aave_1306 | Aave_4564 | PFAM: protein of unknown function UPF0079; KEGG: rfr:Rfer_3302 protein of unknown function UPF0079. | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.605 |
Aave_1306 | Aave_4569 | Aave_1306 | Aave_4569 | PFAM: protein of unknown function UPF0079; KEGG: rfr:Rfer_3302 protein of unknown function UPF0079. | PFAM: peptidase M22, glycoprotease; KEGG: rfr:Rfer_0189 peptidase M22, glycoprotease. | 0.976 |
Aave_1306 | tsaD | Aave_1306 | Aave_2151 | PFAM: protein of unknown function UPF0079; KEGG: rfr:Rfer_3302 protein of unknown function UPF0079. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.891 |
Aave_4560 | Aave_4561 | Aave_4560 | Aave_4561 | PFAM: protein of unknown function DUF306, Meta and HslJ; KEGG: ppr:PBPRA2462 hypothetical protein. | TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: pol:Bpro_4628 thioredoxin. | 0.807 |
Aave_4560 | Aave_4564 | Aave_4560 | Aave_4564 | PFAM: protein of unknown function DUF306, Meta and HslJ; KEGG: ppr:PBPRA2462 hypothetical protein. | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.539 |
Aave_4560 | purE | Aave_4560 | Aave_4562 | PFAM: protein of unknown function DUF306, Meta and HslJ; KEGG: ppr:PBPRA2462 hypothetical protein. | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.633 |
Aave_4560 | purK | Aave_4560 | Aave_4563 | PFAM: protein of unknown function DUF306, Meta and HslJ; KEGG: ppr:PBPRA2462 hypothetical protein. | 5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.619 |
Aave_4561 | Aave_4560 | Aave_4561 | Aave_4560 | TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: pol:Bpro_4628 thioredoxin. | PFAM: protein of unknown function DUF306, Meta and HslJ; KEGG: ppr:PBPRA2462 hypothetical protein. | 0.807 |
Aave_4561 | Aave_4564 | Aave_4561 | Aave_4564 | TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: pol:Bpro_4628 thioredoxin. | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.698 |
Aave_4561 | Aave_4565 | Aave_4561 | Aave_4565 | TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: pol:Bpro_4628 thioredoxin. | Lipase; KEGG: xom:XOO_3175 lipase. | 0.571 |
Aave_4561 | purE | Aave_4561 | Aave_4562 | TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: pol:Bpro_4628 thioredoxin. | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.713 |
Aave_4561 | purK | Aave_4561 | Aave_4563 | TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: pol:Bpro_4628 thioredoxin. | 5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.721 |
Aave_4564 | Aave_1306 | Aave_4564 | Aave_1306 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | PFAM: protein of unknown function UPF0079; KEGG: rfr:Rfer_3302 protein of unknown function UPF0079. | 0.605 |
Aave_4564 | Aave_4560 | Aave_4564 | Aave_4560 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | PFAM: protein of unknown function DUF306, Meta and HslJ; KEGG: ppr:PBPRA2462 hypothetical protein. | 0.539 |
Aave_4564 | Aave_4561 | Aave_4564 | Aave_4561 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: pol:Bpro_4628 thioredoxin. | 0.698 |
Aave_4564 | Aave_4565 | Aave_4564 | Aave_4565 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Lipase; KEGG: xom:XOO_3175 lipase. | 0.713 |
Aave_4564 | Aave_4569 | Aave_4564 | Aave_4569 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | PFAM: peptidase M22, glycoprotease; KEGG: rfr:Rfer_0189 peptidase M22, glycoprotease. | 0.606 |
Aave_4564 | glmS | Aave_4564 | Aave_4036 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.464 |
Aave_4564 | glyA | Aave_4564 | Aave_2992 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.745 |
Aave_4564 | purE | Aave_4564 | Aave_4562 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.850 |