Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Aave_4654KEGG: pol:Bpro_4653 signal transduction histidine kinase, nitrogen specific, NtrB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. (707 aa)    
Predicted Functional Partners:
Aave_4653
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: pol:Bpro_4652 two component transcriptional regulator, LuxR family.
 
 0.994
Aave_3996
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; CHASE3 domain protein; KEGG: ppu:PP_3761 sensor histidine kinase/response regulator.
  
 
 0.967
Aave_2975
PAS/PAC sensor hybrid histidine kinase; KEGG: reu:Reut_B4975 PAS; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
0.947
Aave_4279
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-4 domain protein; KEGG: mag:amb1110 signal transduction histidine kinase.
 
 
 0.935
Aave_4732
Multi-sensor hybrid histidine kinase; KEGG: psb:Psyr_3532 PAS; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein.
  
 
 0.932
Aave_2063
Multi-sensor hybrid histidine kinase; KEGG: mag:amb1841 hypothetical protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
 
 0.918
Aave_2240
PFAM: response regulator receiver; KEGG: xcv:XCV0528 two-component system sensor protein.
  
 
 0.905
Aave_1900
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAC repeat-containing protein; KEGG: ade:Adeh_3183 signal transduction histidine kinase.
 
 
0.889
Aave_3564
KEGG: xcb:XC_1691 sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
0.888
Aave_4656
KEGG: rfr:Rfer_0366 hypothetical protein.
 
     0.874
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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