Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Aave_4656KEGG: rfr:Rfer_0366 hypothetical protein. (1425 aa)    
Predicted Functional Partners:
Aave_4655
PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: pol:Bpro_4654 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase.
 
     0.876
Aave_4654
KEGG: pol:Bpro_4653 signal transduction histidine kinase, nitrogen specific, NtrB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
     0.874
Aave_4653
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: pol:Bpro_4652 two component transcriptional regulator, LuxR family.
       0.791
Aave_1996
PFAM: HemY domain protein; KEGG: pol:Bpro_3661 putative porphyrin biosynthesis related protein.
  
     0.752
glnE
(Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...]
 
     0.752
Aave_4783
PFAM: protein of unknown function DUF1239; KEGG: rfr:Rfer_4235 protein of unknown function DUF1239.
  
     0.737
Aave_0740
KEGG: pol:Bpro_0444 hypothetical protein.
 
     0.726
Aave_3642
KEGG: rfr:Rfer_1293 hypothetical protein.
  
     0.717
cobD-2
Conserved hypothetical protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
  
     0.701
Aave_1997
PFAM: protein of unknown function DUF513, hemX; KEGG: rfr:Rfer_1717 protein of unknown function DUF513, HemX.
  
     0.694
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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