Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Aave_4776TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: nwi:Nwi_2429 diguanylate cyclase. (403 aa)    
Predicted Functional Partners:
Aave_2064
PFAM: response regulator receiver; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: syn:slr2100 two-component response regulator.
 
  
 0.885
Aave_3545
Diguanylate phosphodiesterase; PFAM: EAL domain protein; KEGG: xcb:XC_1411 response regulator.
    0.879
Aave_3096
Diguanylate cyclase/phosphodiesterase with GAF sensor; PFAM: EAL domain protein; GAF domain protein; KEGG: pfl:PFL_1425 GAF domain/GGDEF domain/EAL domain protein.
  
 0.813
Aave_1408
Diguanylate phosphodiesterase; PFAM: EAL domain protein; KEGG: xcb:XC_3163 EAL domain protein.
 
    0.811
Aave_3524
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: rfr:Rfer_3397 two component transcriptional regulator, LuxR family.
 
 
    0.768
Aave_1120
Diguanylate cyclase/phosphodiesterase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: rfr:Rfer_2030 diguanylate cyclase/phosphodiesterase.
  
    0.640
Aave_2927
KEGG: rme:Rmet_2261 putative lipoprotein.
  
   0.562
Aave_0592
KEGG: rfr:Rfer_3329 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region.
 
 
 
 0.554
Aave_2063
Multi-sensor hybrid histidine kinase; KEGG: mag:amb1841 hypothetical protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
 0.550
Aave_0649
KEGG: rfr:Rfer_3572 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
0.545
Your Current Organism:
Acidovorax citrulli
NCBI taxonomy Id: 397945
Other names: A. citrulli AAC00-1, Acidovorax avenae subsp. citrulli AAC00-1, Acidovorax citrulli AAC00-1, Acidovorax citrulli str. AAC00-1, Acidovorax citrulli strain AAC00-1
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