| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cmaq_0135 | srp19 | Cmaq_0135 | Cmaq_0367 | KEGG: pis:Pisl_0572 transcriptional regulator, MarR family. | Ribonucleoprotein complex SRP, Srp19 component; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. | 0.693 |
| Cmaq_0368 | rps8e | Cmaq_0368 | Cmaq_1630 | PFAM: protein of unknown function ATP binding; KEGG: pai:PAE3333 hypothetical protein. | PFAM: Ribosomal protein S8E; KEGG: pis:Pisl_0575 ribosomal protein S8e. | 0.665 |
| Cmaq_0368 | srp19 | Cmaq_0368 | Cmaq_0367 | PFAM: protein of unknown function ATP binding; KEGG: pai:PAE3333 hypothetical protein. | Ribonucleoprotein complex SRP, Srp19 component; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. | 0.925 |
| egsA | ftsY | Cmaq_1971 | Cmaq_0870 | Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.541 |
| egsA | srp19 | Cmaq_1971 | Cmaq_0367 | Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | Ribonucleoprotein complex SRP, Srp19 component; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. | 0.765 |
| egsA | srp54 | Cmaq_1971 | Cmaq_0296 | Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | GTP-binding signal recognition particle SRP54 G- domain; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.621 |
| egsA | tatC | Cmaq_1971 | Cmaq_0725 | Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | Sec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. | 0.573 |
| ftsY | egsA | Cmaq_0870 | Cmaq_1971 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | 0.541 |
| ftsY | srp19 | Cmaq_0870 | Cmaq_0367 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Ribonucleoprotein complex SRP, Srp19 component; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. | 0.887 |
| ftsY | srp54 | Cmaq_0870 | Cmaq_0296 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | GTP-binding signal recognition particle SRP54 G- domain; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.996 |
| ftsY | tatC | Cmaq_0870 | Cmaq_0725 | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Sec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. | 0.744 |
| lysJ | rps8e | Cmaq_0767 | Cmaq_1630 | Aminotransferase class-III; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. | PFAM: Ribosomal protein S8E; KEGG: pis:Pisl_0575 ribosomal protein S8e. | 0.676 |
| lysJ | srp19 | Cmaq_0767 | Cmaq_0367 | Aminotransferase class-III; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. | Ribonucleoprotein complex SRP, Srp19 component; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. | 0.676 |
| lysJ | uppS | Cmaq_0767 | Cmaq_0786 | Aminotransferase class-III; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. | Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. | 0.697 |
| rps3ae | rps8e | Cmaq_1755 | Cmaq_1630 | PFAM: ribosomal protein S3Ae; KEGG: pis:Pisl_0771 ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family. | PFAM: Ribosomal protein S8E; KEGG: pis:Pisl_0575 ribosomal protein S8e. | 0.967 |
| rps3ae | srp19 | Cmaq_1755 | Cmaq_0367 | PFAM: ribosomal protein S3Ae; KEGG: pis:Pisl_0771 ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family. | Ribonucleoprotein complex SRP, Srp19 component; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP. | 0.725 |
| rps3ae | srp54 | Cmaq_1755 | Cmaq_0296 | PFAM: ribosomal protein S3Ae; KEGG: pis:Pisl_0771 ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family. | GTP-binding signal recognition particle SRP54 G- domain; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.579 |
| rps8e | Cmaq_0368 | Cmaq_1630 | Cmaq_0368 | PFAM: Ribosomal protein S8E; KEGG: pis:Pisl_0575 ribosomal protein S8e. | PFAM: protein of unknown function ATP binding; KEGG: pai:PAE3333 hypothetical protein. | 0.665 |
| rps8e | lysJ | Cmaq_1630 | Cmaq_0767 | PFAM: Ribosomal protein S8E; KEGG: pis:Pisl_0575 ribosomal protein S8e. | Aminotransferase class-III; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. | 0.676 |
| rps8e | rps3ae | Cmaq_1630 | Cmaq_1755 | PFAM: Ribosomal protein S8E; KEGG: pis:Pisl_0575 ribosomal protein S8e. | PFAM: ribosomal protein S3Ae; KEGG: pis:Pisl_0771 ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family. | 0.967 |