STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cobBSilent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily. (257 aa)    
Predicted Functional Partners:
Cmaq_0276
TIGRFAM: cytidyltransferase-related domain; PFAM: cytidylyltransferase; KEGG: pis:Pisl_0898 cytidyltransferase-related domain.
   
 
  0.959
Cmaq_1647
TIGRFAM: cytidyltransferase-related domain; nicotinamide-nucleotide adenylyltransferase; PFAM: cytidylyltransferase; KEGG: pis:Pisl_1561 nicotinamide-nucleotide adenylyltransferase.
   
 
  0.959
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
    
 0.932
nadK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.920
Cmaq_1331
ATP-NAD/AcoX kinase; PFAM: regulatory protein ArsR; ATP-NAD/AcoX kinase; KEGG: pai:PAE3116 hypothetical protein.
  
 
 0.920
Cmaq_1949
PFAM: histone deacetylase superfamily; KEGG: pis:Pisl_0381 histone deacetylase superfamily.
   
 0.846
Cmaq_0204
PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: pai:PAE1996 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.835
Cmaq_0470
PFAM: Carboxymuconolactone decarboxylase; Cupin domain protein; Cupin 2 conserved barrel domain protein; KEGG: rfr:Rfer_2441 carboxymuconolactone decarboxylase.
  
    0.822
Cmaq_0256
TIGRFAM: acetate--CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: pis:Pisl_0270 acetate--CoA ligase.
   
 0.715
Cmaq_1738
TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: sai:Saci_2375 isocitrate dehydrogenase.
   
 0.713
Your Current Organism:
Caldivirga maquilingensis
NCBI taxonomy Id: 397948
Other names: C. maquilingensis IC-167, Caldivirga maquilingensis DSM 13496, Caldivirga maquilingensis IC-167, Caldivirga maquilingensis JCM 10307, Caldivirga maquilingensis str. IC-167, Caldivirga maquilingensis strain IC-167
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