Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Cmaq_0620PFAM: DEAD_2 domain protein; SMART: DEXDc2; helicase c2; KEGG: pai:PAE2991 hypothetical protein. (634 aa)    
Predicted Functional Partners:
Cmaq_0822
PFAM: helicase domain protein; type III restriction protein res subunit; SMART: Hedgehog/intein hint domain protein; DEAD-like helicases; KEGG: pai:PAE1611 helicase, possible DNA repair rad25.
   
 0.971
tfe
Transcription factor TFIIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongatio [...]
   
 0.956
Cmaq_0449
RNA polymerase Rpb2 domain 6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.927
Cmaq_1166
PFAM: RNA polymerase dimerisation; RNA polymerase insert; SMART: RNA polymerase RpoA/D/Rpb3-type; KEGG: pis:Pisl_0697 RNA polymerase, insert.
  
 0.925
tbp
2-alkenal reductase; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
 
 0.923
fen
XPG I; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genom [...]
 
 0.918
rpoH
RNA polymerase Rpb5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
    
  0.905
Cmaq_0242
SMART: RNA polymerase Rbp10; KEGG: pis:Pisl_0899 RNA polymerase Rbp10.
    
  0.904
rpoN
RNA polymerase, N/8 Kd subunits; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.
    
 0.904
Cmaq_0462
PFAM: RNA polymerase Rpb6; KEGG: pai:PAE3271 DNA-directed RNA polymerase subunit.
   
  0.890
Your Current Organism:
Caldivirga maquilingensis
NCBI taxonomy Id: 397948
Other names: C. maquilingensis IC-167, Caldivirga maquilingensis DSM 13496, Caldivirga maquilingensis IC-167, Caldivirga maquilingensis JCM 10307, Caldivirga maquilingensis str. IC-167, Caldivirga maquilingensis strain IC-167
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