STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nep1Suppressor Mra1; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. (228 aa)    
Predicted Functional Partners:
rps6e
PFAM: Ribosomal protein S6e; KEGG: pai:PAE1505 ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.
   
  0.999
rps5
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
   
  0.999
Cmaq_0980
PFAM: KH type 1 domain protein; KEGG: hbu:Hbut_1405 universally conserved protein.
  
 0.999
rps4
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
  0.999
Cmaq_1284
PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC; KEGG: pai:PAE3232 nop family pre-rRNA processing protein.
  
 
 0.999
rps11
Ribosomal protein S11; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
   
 0.999
csl4
RNA binding S1 domain protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.
 
 0.958
rtcA
RNA-3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
  
 
 0.946
rps17
Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
  
  0.933
rps7
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.
  
 0.930
Your Current Organism:
Caldivirga maquilingensis
NCBI taxonomy Id: 397948
Other names: C. maquilingensis IC-167, Caldivirga maquilingensis DSM 13496, Caldivirga maquilingensis IC-167, Caldivirga maquilingensis JCM 10307, Caldivirga maquilingensis str. IC-167, Caldivirga maquilingensis strain IC-167
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