STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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purLPhosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (724 aa)    
Predicted Functional Partners:
purQ
Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
 0.999
Cmaq_0662
KEGG: sai:Saci_1608 hypothetical protein.
  
 0.999
Cmaq_0665
TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: pai:PAE0221 phosphoribosylformylglycinamidine cyclo-ligase (AIRS) (purM).
 
 
 0.999
purT
ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.
  
 
 0.998
purF
Glutamine amidotransferase class-II; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
 
 0.998
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
 
 
 0.998
Cmaq_0663
TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; KEGG: pai:PAE0216 phosphoribosylglycinamide synthetase (GARS) (purD).
  
 0.992
Cmaq_0666
Amidophosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: sso:SSO0633 amidophosphoribosyltransferase (glutamine phosphoribosylpyrophosphate amidotransferase) (ATase) (GPAT) (PurF-2).
 
 0.991
purC
PFAM: SAICAR synthetase; KEGG: pis:Pisl_0105 phosphoribosylaminoimidazolesuccinocarboxamide synthase.
 
 
 0.989
purK
Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
 
  
 0.978
Your Current Organism:
Caldivirga maquilingensis
NCBI taxonomy Id: 397948
Other names: C. maquilingensis IC-167, Caldivirga maquilingensis DSM 13496, Caldivirga maquilingensis IC-167, Caldivirga maquilingensis JCM 10307, Caldivirga maquilingensis str. IC-167, Caldivirga maquilingensis strain IC-167
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