Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Cmaq_0792PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: pis:Pisl_0566 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (317 aa)    
Predicted Functional Partners:
Cmaq_0793
PFAM: aminotransferase class V; KEGG: pis:Pisl_0567 aminotransferase, class V.
 
  
 0.955
Cmaq_0729
PFAM: Phosphoglycerate mutase; KEGG: pto:PTO1423 phosphoglycerate mutase/fructose-2,6-bisphosphatase.
 
 
 0.943
Cmaq_0340
TIGRFAM: phosphonopyruvate decarboxylase-related protein; PFAM: metalloenzyme domain protein; KEGG: tpe:Tpen_1046 phosphonopyruvate decarboxylase-related protein.
    
 0.923
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.772
Cmaq_1172
TIGRFAM: isopropylmalate/isohomocitrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: sso:SSO0723 3-isopropylmalate dehydrogenase.
  
  
 0.732
Cmaq_0731
PFAM: homoserine dehydrogenase; KEGG: sto:ST1519 homoserine dehydrogenase.
 
 
 0.627
Cmaq_1364
Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: pis:Pisl_0881 cystathionine gamma-synthase.
 
 
 0.621
Cmaq_1593
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: sto:ST1380 cysteine synthase.
  
 
 0.621
rpl6
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
   0.598
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.588
Your Current Organism:
Caldivirga maquilingensis
NCBI taxonomy Id: 397948
Other names: C. maquilingensis IC-167, Caldivirga maquilingensis DSM 13496, Caldivirga maquilingensis IC-167, Caldivirga maquilingensis JCM 10307, Caldivirga maquilingensis str. IC-167, Caldivirga maquilingensis strain IC-167
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