STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tfbTranscription factor TFIIB cyclin-related; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (336 aa)    
Predicted Functional Partners:
tbp
2-alkenal reductase; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
  
 0.956
Cmaq_1166
PFAM: RNA polymerase dimerisation; RNA polymerase insert; SMART: RNA polymerase RpoA/D/Rpb3-type; KEGG: pis:Pisl_0697 RNA polymerase, insert.
  
 0.929
Cmaq_1632
PFAM: Zinc finger TFIIB-type domain protein; Transcription factor TFIIB cyclin-related; KEGG: tko:TK1280 transcription initiation factor IIB.
  
  
 
0.915
rpoN
RNA polymerase, N/8 Kd subunits; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.
  
 0.895
Cmaq_0449
RNA polymerase Rpb2 domain 6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.894
Cmaq_0822
PFAM: helicase domain protein; type III restriction protein res subunit; SMART: Hedgehog/intein hint domain protein; DEAD-like helicases; KEGG: pai:PAE1611 helicase, possible DNA repair rad25.
  
 
 0.890
Cmaq_0620
PFAM: DEAD_2 domain protein; SMART: DEXDc2; helicase c2; KEGG: pai:PAE2991 hypothetical protein.
  
 
 0.887
Cmaq_0242
SMART: RNA polymerase Rbp10; KEGG: pis:Pisl_0899 RNA polymerase Rbp10.
   
 0.880
tfe
Transcription factor TFIIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongatio [...]
    
 0.875
rpoH
RNA polymerase Rpb5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
    
 0.875
Your Current Organism:
Caldivirga maquilingensis
NCBI taxonomy Id: 397948
Other names: C. maquilingensis IC-167, Caldivirga maquilingensis DSM 13496, Caldivirga maquilingensis IC-167, Caldivirga maquilingensis JCM 10307, Caldivirga maquilingensis str. IC-167, Caldivirga maquilingensis strain IC-167
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