| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cmaq_0637 | Cmaq_0928 | Cmaq_0637 | Cmaq_0928 | PFAM: Polyprenyl synthetase; KEGG: pai:PAE1013 dimethylallyltranstransferase / geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.580 |
| Cmaq_0637 | Cmaq_0958 | Cmaq_0637 | Cmaq_0958 | PFAM: Polyprenyl synthetase; KEGG: pai:PAE1013 dimethylallyltranstransferase / geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | PFAM: UbiA prenyltransferase; KEGG: pai:PAE1784 hypothetical 4-hydroxybenzoate octaprenyltransferase. | 0.626 |
| Cmaq_0637 | egsA | Cmaq_0637 | Cmaq_1971 | PFAM: Polyprenyl synthetase; KEGG: pai:PAE1013 dimethylallyltranstransferase / geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | 0.494 |
| Cmaq_0928 | Cmaq_0637 | Cmaq_0928 | Cmaq_0637 | Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | PFAM: Polyprenyl synthetase; KEGG: pai:PAE1013 dimethylallyltranstransferase / geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | 0.580 |
| Cmaq_0928 | Cmaq_0929 | Cmaq_0928 | Cmaq_0929 | Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | PFAM: Protein of unknown function DUF701, zinc-binding putative; KEGG: pis:Pisl_0444 hypothetical protein. | 0.895 |
| Cmaq_0928 | Cmaq_0930 | Cmaq_0928 | Cmaq_0930 | Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | PFAM: PBS lyase HEAT domain protein repeat-containing protein; Peptidase M1 membrane alanine aminopeptidase; KEGG: pis:Pisl_1642 peptidase M1, membrane alanine aminopeptidase. | 0.569 |
| Cmaq_0928 | Cmaq_0932 | Cmaq_0928 | Cmaq_0932 | Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | PFAM: Protein of unknown function UPF0147; KEGG: hbu:Hbut_1631 hypothetical protein; Belongs to the UPF0147 family. | 0.520 |
| Cmaq_0928 | Cmaq_0958 | Cmaq_0928 | Cmaq_0958 | Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | PFAM: UbiA prenyltransferase; KEGG: pai:PAE1784 hypothetical 4-hydroxybenzoate octaprenyltransferase. | 0.995 |
| Cmaq_0928 | Cmaq_1312 | Cmaq_0928 | Cmaq_1312 | Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | PFAM: protein of unknown function DUF123; KEGG: mst:Msp_1119 hypothetical protein. | 0.561 |
| Cmaq_0928 | carS | Cmaq_0928 | Cmaq_0732 | Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Protein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.776 |
| Cmaq_0928 | egsA | Cmaq_0928 | Cmaq_1971 | Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | 0.975 |
| Cmaq_0928 | rpiA | Cmaq_0928 | Cmaq_0742 | Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.668 |
| Cmaq_0928 | tpiA | Cmaq_0928 | Cmaq_0703 | Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.520 |
| Cmaq_0929 | Cmaq_0928 | Cmaq_0929 | Cmaq_0928 | PFAM: Protein of unknown function DUF701, zinc-binding putative; KEGG: pis:Pisl_0444 hypothetical protein. | Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.895 |
| Cmaq_0929 | Cmaq_0930 | Cmaq_0929 | Cmaq_0930 | PFAM: Protein of unknown function DUF701, zinc-binding putative; KEGG: pis:Pisl_0444 hypothetical protein. | PFAM: PBS lyase HEAT domain protein repeat-containing protein; Peptidase M1 membrane alanine aminopeptidase; KEGG: pis:Pisl_1642 peptidase M1, membrane alanine aminopeptidase. | 0.655 |
| Cmaq_0930 | Cmaq_0928 | Cmaq_0930 | Cmaq_0928 | PFAM: PBS lyase HEAT domain protein repeat-containing protein; Peptidase M1 membrane alanine aminopeptidase; KEGG: pis:Pisl_1642 peptidase M1, membrane alanine aminopeptidase. | Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.569 |
| Cmaq_0930 | Cmaq_0929 | Cmaq_0930 | Cmaq_0929 | PFAM: PBS lyase HEAT domain protein repeat-containing protein; Peptidase M1 membrane alanine aminopeptidase; KEGG: pis:Pisl_1642 peptidase M1, membrane alanine aminopeptidase. | PFAM: Protein of unknown function DUF701, zinc-binding putative; KEGG: pis:Pisl_0444 hypothetical protein. | 0.655 |
| Cmaq_0932 | Cmaq_0928 | Cmaq_0932 | Cmaq_0928 | PFAM: Protein of unknown function UPF0147; KEGG: hbu:Hbut_1631 hypothetical protein; Belongs to the UPF0147 family. | Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.520 |
| Cmaq_0932 | carS | Cmaq_0932 | Cmaq_0732 | PFAM: Protein of unknown function UPF0147; KEGG: hbu:Hbut_1631 hypothetical protein; Belongs to the UPF0147 family. | Protein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.442 |
| Cmaq_0958 | Cmaq_0637 | Cmaq_0958 | Cmaq_0637 | PFAM: UbiA prenyltransferase; KEGG: pai:PAE1784 hypothetical 4-hydroxybenzoate octaprenyltransferase. | PFAM: Polyprenyl synthetase; KEGG: pai:PAE1013 dimethylallyltranstransferase / geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | 0.626 |