STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (285 aa)    
Predicted Functional Partners:
Cmaq_0501
PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: pau:PA14_17730 putative carbon-nitrogen hydrolase family protein.
   
 0.960
nadK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
  
 0.940
Cmaq_0276
TIGRFAM: cytidyltransferase-related domain; PFAM: cytidylyltransferase; KEGG: pis:Pisl_0898 cytidyltransferase-related domain.
 
  
 0.938
Cmaq_1331
ATP-NAD/AcoX kinase; PFAM: regulatory protein ArsR; ATP-NAD/AcoX kinase; KEGG: pai:PAE3116 hypothetical protein.
 
  
 0.936
Cmaq_1647
TIGRFAM: cytidyltransferase-related domain; nicotinamide-nucleotide adenylyltransferase; PFAM: cytidylyltransferase; KEGG: pis:Pisl_1561 nicotinamide-nucleotide adenylyltransferase.
 
  
 0.935
cobB
Silent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily.
    
 0.932
Cmaq_0933
PFAM: Quinolinate phosphoribosyl transferase; KEGG: pis:Pisl_0389 quinolinate phosphoribosyl transferase.
 
  
 0.762
Cmaq_0224
Nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
     
 0.582
Cmaq_0802
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pai:PAE3086 oligopeptide ABC transporter, permease protein.
 
  
 0.575
Cmaq_1792
TIGRFAM: quinolinate synthetase complex, A subunit; PFAM: Quinolinate synthetase A; KEGG: sto:ST1197 hypothetical quinolinate synthetase A.
  
  
 0.544
Your Current Organism:
Caldivirga maquilingensis
NCBI taxonomy Id: 397948
Other names: C. maquilingensis IC-167, Caldivirga maquilingensis DSM 13496, Caldivirga maquilingensis IC-167, Caldivirga maquilingensis JCM 10307, Caldivirga maquilingensis str. IC-167, Caldivirga maquilingensis strain IC-167
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