Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Cmaq_1133Diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. (337 aa)    
Predicted Functional Partners:
fusA
Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]
    
 0.983
dphB
Diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.
  
 0.943
csl4
RNA binding S1 domain protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.
 
    0.805
Cmaq_0577
PFAM: putative RNA methylase; KEGG: pai:PAE0261 methylase, conjectural.
 
     0.798
Cmaq_1539
KEGG: pai:PAE1978 DNA-directed RNA polymerase subunit L.
  
    0.748
rpl10e
PFAM: Ribosomal protein L10E; KEGG: pis:Pisl_0917 ribosomal protein L10E; Belongs to the universal ribosomal protein uL16 family.
   
   0.723
Cmaq_0399
TIGRFAM: transcription factor S; PFAM: Transcription factor TFIIS; DNA-directed RNA polymerase, M/15 kDa subunit; KEGG: sto:ST2261 hypothetical DNA-directed RNA polymerase subunit M; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
  
    0.713
Cmaq_1530
TIGRFAM: putative ATP binding protein; PFAM: protein of unknown function DUF71 ATP-binding region; KEGG: sto:ST2048 hypothetical protein.
  
   
 0.680
rpl37ae
Ribosomal protein L37a; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
 
  
 0.670
Cmaq_0809
Transketolase central region; PFAM: Transketolase domain protein; Transketolase central region; KEGG: sai:Saci_0181 pyridine-binding domain transketolase.
 
     0.630
Your Current Organism:
Caldivirga maquilingensis
NCBI taxonomy Id: 397948
Other names: C. maquilingensis IC-167, Caldivirga maquilingensis DSM 13496, Caldivirga maquilingensis IC-167, Caldivirga maquilingensis JCM 10307, Caldivirga maquilingensis str. IC-167, Caldivirga maquilingensis strain IC-167
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