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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
hisBPFAM: imidazoleglycerol-phosphate dehydratase; KEGG: plt:Plut_0718 imidazoleglycerol-phosphate dehydratase. (192 aa)    
Predicted Functional Partners:
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
 
 
 0.999
hisH
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
 
 
 0.999
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
 
 0.999
Cmaq_1410
PFAM: aminotransferase class I and II; KEGG: pai:PAE0958 histidinol-phosphate aminotransferase.
 
 0.999
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
 
  
 0.998
Cmaq_1401
PFAM: histidine biosynthesis protein; KEGG: pai:PAE0991 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Belongs to the HisA/HisF family.
 
  
 0.996
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
 
  
 0.989
hisE
PFAM: phosphoribosyl-ATP pyrophosphohydrolase; KEGG: pai:PAE0986 phosphoribosyl-ATP pyrophosphohydrolase.
 
  
 0.979
Cmaq_0512
PFAM: aminotransferase class I and II; KEGG: cno:NT01CX_2083 L-threonine-O-3-phosphate decarboxylase, putative.
 
  
 0.884
Cmaq_1316
KEGG: pis:Pisl_1212 aminotransferase, class I and II.
  
  
 0.813
Your Current Organism:
Caldivirga maquilingensis
NCBI taxonomy Id: 397948
Other names: C. maquilingensis IC-167, Caldivirga maquilingensis DSM 13496, Caldivirga maquilingensis IC-167, Caldivirga maquilingensis JCM 10307, Caldivirga maquilingensis str. IC-167, Caldivirga maquilingensis strain IC-167
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