| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cmaq_0455 | egsA | Cmaq_0455 | Cmaq_1971 | PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: pai:PAE0820 mRNA 3'-end processing factor, conjectural. | Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | 0.699 |
| Cmaq_0809 | aroB | Cmaq_0809 | Cmaq_0806 | Transketolase central region; PFAM: Transketolase domain protein; Transketolase central region; KEGG: sai:Saci_0181 pyridine-binding domain transketolase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.933 |
| Cmaq_0809 | egsA | Cmaq_0809 | Cmaq_1971 | Transketolase central region; PFAM: Transketolase domain protein; Transketolase central region; KEGG: sai:Saci_0181 pyridine-binding domain transketolase. | Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | 0.720 |
| Cmaq_0928 | Cmaq_0958 | Cmaq_0928 | Cmaq_0958 | Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | PFAM: UbiA prenyltransferase; KEGG: pai:PAE1784 hypothetical 4-hydroxybenzoate octaprenyltransferase. | 0.995 |
| Cmaq_0928 | carS | Cmaq_0928 | Cmaq_0732 | Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Protein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.776 |
| Cmaq_0928 | egsA | Cmaq_0928 | Cmaq_1971 | Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | 0.975 |
| Cmaq_0958 | Cmaq_0928 | Cmaq_0958 | Cmaq_0928 | PFAM: UbiA prenyltransferase; KEGG: pai:PAE1784 hypothetical 4-hydroxybenzoate octaprenyltransferase. | Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.995 |
| Cmaq_0958 | carS | Cmaq_0958 | Cmaq_0732 | PFAM: UbiA prenyltransferase; KEGG: pai:PAE1784 hypothetical 4-hydroxybenzoate octaprenyltransferase. | Protein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.975 |
| Cmaq_0958 | egsA | Cmaq_0958 | Cmaq_1971 | PFAM: UbiA prenyltransferase; KEGG: pai:PAE1784 hypothetical 4-hydroxybenzoate octaprenyltransferase. | Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | 0.718 |
| Cmaq_1799 | egsA | Cmaq_1799 | Cmaq_1971 | PFAM: FAD dependent oxidoreductase; KEGG: sso:SSO2526 glycerol-3-phosphate dehydrogenase. | Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | 0.928 |
| aroB | Cmaq_0809 | Cmaq_0806 | Cmaq_0809 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Transketolase central region; PFAM: Transketolase domain protein; Transketolase central region; KEGG: sai:Saci_0181 pyridine-binding domain transketolase. | 0.933 |
| aroB | egsA | Cmaq_0806 | Cmaq_1971 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | 0.702 |
| carS | Cmaq_0928 | Cmaq_0732 | Cmaq_0928 | Protein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.776 |
| carS | Cmaq_0958 | Cmaq_0732 | Cmaq_0958 | Protein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | PFAM: UbiA prenyltransferase; KEGG: pai:PAE1784 hypothetical 4-hydroxybenzoate octaprenyltransferase. | 0.975 |
| carS | egsA | Cmaq_0732 | Cmaq_1971 | Protein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | 0.752 |
| carS | mvk | Cmaq_0732 | Cmaq_0966 | Protein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.694 |
| egsA | Cmaq_0455 | Cmaq_1971 | Cmaq_0455 | Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: pai:PAE0820 mRNA 3'-end processing factor, conjectural. | 0.699 |
| egsA | Cmaq_0809 | Cmaq_1971 | Cmaq_0809 | Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | Transketolase central region; PFAM: Transketolase domain protein; Transketolase central region; KEGG: sai:Saci_0181 pyridine-binding domain transketolase. | 0.720 |
| egsA | Cmaq_0928 | Cmaq_1971 | Cmaq_0928 | Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.975 |
| egsA | Cmaq_0958 | Cmaq_1971 | Cmaq_0958 | Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. | PFAM: UbiA prenyltransferase; KEGG: pai:PAE1784 hypothetical 4-hydroxybenzoate octaprenyltransferase. | 0.718 |