STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDI02140.1Serine O-acetyltransferase. (185 aa)    
Predicted Functional Partners:
SDI02174.1
Cysteine synthase A.
 
 0.999
cysS
cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.995
SDJ03214.1
Cysteine synthase.
  
 0.925
SDJ25897.1
Homoserine dehydrogenase.
  
  
 0.900
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.891
SDJ25813.1
Homoserine kinase.
     
 0.890
SDI02234.1
CDP-diacylglycerol---serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
    
  0.889
SDI02336.1
L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.876
SDI02367.1
L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.876
SDH97832.1
Protein-tyrosine phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
  0.823
Your Current Organism:
Proteiniclasticum ruminis
NCBI taxonomy Id: 398199
Other names: AS 1.5057, Clostridium sp. D3RC-3r, DSM 24773, JCM 14817, P. ruminis, Proteiniclasticum ruminis Zhang et al. 2010, strain D3RC-2
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