STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDI19912.1Protein of unknown function. (192 aa)    
Predicted Functional Partners:
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.791
SDI82672.1
acetyl-CoA carboxylase carboxyl transferase subunit alpha/acetyl-CoA carboxylase carboxyl transferase subunit beta.
   
  0.779
SDI94413.1
Tetratricopeptide repeat-containing protein.
 
    0.774
SDI75109.1
Tetratricopeptide repeat-containing protein.
  
     0.763
SDI02518.1
Adenylate cyclase, class 2.
  
     0.753
SDH92089.1
Hypothetical protein.
  
     0.721
SDI94491.1
Uncharacterized membrane protein YkvA, DUF1232 family.
  
     0.714
SDI00023.1
Signal transduction histidine kinase.
   
 
 0.708
SDH98658.1
Penicillin-binding protein 2.
  
     0.678
SDI77314.1
Membrane protein implicated in regulation of membrane protease activity.
  
     0.673
Your Current Organism:
Proteiniclasticum ruminis
NCBI taxonomy Id: 398199
Other names: AS 1.5057, Clostridium sp. D3RC-3r, DSM 24773, JCM 14817, P. ruminis, Proteiniclasticum ruminis Zhang et al. 2010, strain D3RC-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.