node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDI32080.1 | SDI32119.1 | SAMN05421804_10245 | SAMN05421804_10246 | 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis. | single-stranded-DNA-specific exonuclease. | 0.654 |
SDI32080.1 | polA | SAMN05421804_10245 | SAMN05421804_10572 | 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.471 |
SDI32119.1 | SDI32080.1 | SAMN05421804_10246 | SAMN05421804_10245 | single-stranded-DNA-specific exonuclease. | 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis. | 0.654 |
SDI32119.1 | SDI81632.1 | SAMN05421804_10246 | SAMN05421804_104252 | single-stranded-DNA-specific exonuclease. | ATP-dependent DNA helicase RecQ. | 0.629 |
SDI32119.1 | mutL | SAMN05421804_10246 | SAMN05421804_10439 | single-stranded-DNA-specific exonuclease. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.665 |
SDI32119.1 | polA | SAMN05421804_10246 | SAMN05421804_10572 | single-stranded-DNA-specific exonuclease. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.550 |
SDI32119.1 | priA | SAMN05421804_10246 | SAMN05421804_101161 | single-stranded-DNA-specific exonuclease. | Replication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.560 |
SDI32119.1 | recG | SAMN05421804_10246 | SAMN05421804_101147 | single-stranded-DNA-specific exonuclease. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.560 |
SDI32119.1 | recO | SAMN05421804_10246 | SAMN05421804_101300 | single-stranded-DNA-specific exonuclease. | DNA repair protein RecO (recombination protein O); Involved in DNA repair and RecF pathway recombination. | 0.570 |
SDI32119.1 | secD | SAMN05421804_10246 | SAMN05421804_101215 | single-stranded-DNA-specific exonuclease. | SecD/SecF fusion protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.571 |
SDI32119.1 | topA | SAMN05421804_10246 | SAMN05421804_101118 | single-stranded-DNA-specific exonuclease. | DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.662 |
SDI32119.1 | topB | SAMN05421804_10246 | SAMN05421804_101800 | single-stranded-DNA-specific exonuclease. | DNA topoisomerase-3; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.608 |
SDI81632.1 | SDI32119.1 | SAMN05421804_104252 | SAMN05421804_10246 | ATP-dependent DNA helicase RecQ. | single-stranded-DNA-specific exonuclease. | 0.629 |
SDI81632.1 | mutL | SAMN05421804_104252 | SAMN05421804_10439 | ATP-dependent DNA helicase RecQ. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.953 |
SDI81632.1 | polA | SAMN05421804_104252 | SAMN05421804_10572 | ATP-dependent DNA helicase RecQ. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.998 |
SDI81632.1 | recG | SAMN05421804_104252 | SAMN05421804_101147 | ATP-dependent DNA helicase RecQ. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.716 |
SDI81632.1 | recO | SAMN05421804_104252 | SAMN05421804_101300 | ATP-dependent DNA helicase RecQ. | DNA repair protein RecO (recombination protein O); Involved in DNA repair and RecF pathway recombination. | 0.497 |
SDI81632.1 | topA | SAMN05421804_104252 | SAMN05421804_101118 | ATP-dependent DNA helicase RecQ. | DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.998 |
SDI81632.1 | topB | SAMN05421804_104252 | SAMN05421804_101800 | ATP-dependent DNA helicase RecQ. | DNA topoisomerase-3; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.999 |
mutL | SDI32119.1 | SAMN05421804_10439 | SAMN05421804_10246 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | single-stranded-DNA-specific exonuclease. | 0.665 |