STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDJ31583.1Hypothetical protein. (73 aa)    
Predicted Functional Partners:
SDJ31628.1
Hypothetical protein.
 
     0.920
SDJ31542.1
Hypothetical protein.
       0.457
SDJ18730.1
2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase.
  
     0.434
SDH97048.1
Hypothetical protein.
 
     0.433
SDI53745.1
Phosphoglycerol transferase MdoB.
  
     0.421
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.404
SDJ31719.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.404
Your Current Organism:
Proteiniclasticum ruminis
NCBI taxonomy Id: 398199
Other names: AS 1.5057, Clostridium sp. D3RC-3r, DSM 24773, JCM 14817, P. ruminis, Proteiniclasticum ruminis Zhang et al. 2010, strain D3RC-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.