Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A251LS06Uncharacterized protein. (647 aa)    
Predicted Functional Partners:
A0A251KGU3
Uncharacterized protein.
 
 
 0.989
A0A2C9UNT5
Uncharacterized protein.
  
 
 0.944
A0A2C9UF28
ATP-grasp domain-containing protein.
    
 0.930
A0A2C9VS34
Uncharacterized protein.
    
 0.906
A0A2C9WQU8
Uncharacterized protein.
    
 0.906
THI1
Thiamine thiazole synthase, chloroplastic; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; B [...]
  
  
 0.902
A0A251KED3
TENA_THI-4 domain-containing protein.
  
 
 0.883
A0A2C9VCD6
Uncharacterized protein.
  
 
 0.883
A0A2C9VHT6
Uncharacterized protein.
  
 
 0.883
A0A2C9VV67
Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family.
     
 0.786
Your Current Organism:
Manihot esculenta
NCBI taxonomy Id: 3983
Other names: M. esculenta, Manihot esculenta Crantz, Manihot utilissima, cassava, manioc, tapioca, yuca
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