Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
Experiments
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[Homology]
Score
A0A2C9VSE2Protein kinase domain-containing protein. (668 aa)    
Predicted Functional Partners:
A0A2C9VCX5
Uncharacterized protein; Belongs to the cyclin family.
   
 
 0.788
A0A251L619
Protein kinase domain-containing protein.
    
 0.766
A0A2C9W7S6
Uncharacterized protein.
   
 
 0.763
A0A2C9WBK2
Uncharacterized protein.
   
 
 0.763
A0A2C9U5J2
Uncharacterized protein.
   
   0.720
A0A2C9U8S9
Uncharacterized protein.
   
   0.720
A0A2C9UNR4
Uncharacterized protein; Belongs to the cyclin family.
     
 0.715
A0A2C9WGV1
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
      
 0.649
A0A251K2X0
Uncharacterized protein.
     
  0.598
A0A2C9UR21
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
  0.557
Your Current Organism:
Manihot esculenta
NCBI taxonomy Id: 3983
Other names: M. esculenta, Manihot esculenta Crantz, Manihot utilissima, cassava, manioc, tapioca, yuca
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