STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFM62542.1tRNA 2-thiocytidine biosynthesis protein TtcA; Belongs to the TtcA family. (251 aa)    
Predicted Functional Partners:
SFM74930.1
Glycosyltransferase, GT2 family.
  
 
 0.942
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.918
SFM91158.1
Sulfur carrier protein ThiS (thiamine biosynthesis).
  
 
 0.832
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.805
SFN01564.1
Glutamate synthase (NADPH) GltB3 subunit.
    
  0.784
SFM89657.1
Uncharacterized protein.
 
    0.757
SFM62562.1
Hypothetical protein.
       0.689
SFM62582.1
Uncharacterized conserved protein YeaO, DUF488 family.
       0.689
hisH
Glutamine amidotransferase / cyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF; Belongs to the HisA/HisF family.
  
 
 0.684
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
  
 0.588
Your Current Organism:
Thermodesulforhabdus norvegica
NCBI taxonomy Id: 39841
Other names: DSM 9990, Desulforhabdus acetothermus, T. norvegica, Thermodesulforhabdus norvegicus, strain A8444
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.