STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpBTryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (453 aa)    
Predicted Functional Partners:
trpA
Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
 0.999
trpC
Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
 
 
 0.971
trpB-2
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
 
0.887
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
  0.859
trpF
Phosphoribosylanthranilate isomerase; Belongs to the TrpF family.
   
 0.696
SFM39474.1
Threonine dehydratase.
     
 0.605
SFM85771.1
tRNA nucleotidyltransferase (CCA-adding enzyme); Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
    
  0.581
SFM49490.1
Homoserine dehydrogenase.
    
  0.580
SFM74481.1
Putative sulfite reductase-associated electron transfer protein DsrP.
       0.538
SFM74520.1
Putative sulfite reductase-associated electron transfer protein DsrO.
       0.497
Your Current Organism:
Thermodesulforhabdus norvegica
NCBI taxonomy Id: 39841
Other names: DSM 9990, Desulforhabdus acetothermus, T. norvegica, Thermodesulforhabdus norvegicus, strain A8444
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.