SFN11022.1 protein (Thermodesulforhabdus norvegica)

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second shell of interactors

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filled nodes:
a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

SFN11022.1

Uncharacterized protein involved in exopolysaccharide biosynthesis. (496 aa)

Predicted Functional Partners:

SFN10997.1

0.999

SFN10948.1

0.997

SFM81084.1

0.992

SFM74930.1

0.954

SFN11038.1

0.924

SFN10969.1

0.811

SFN11064.1

0.713

SFN07572.1

0.708

SFN05777.1

0.672

SFM66643.1

0.616

Your Current Organism:

Thermodesulforhabdus norvegica

NCBI taxonomy Id: 39841
Other names: DSM 9990, Desulforhabdus acetothermus, T. norvegica, Thermodesulforhabdus norvegicus, strain A8444

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SFM66643.1	SFM74930.1	SAMN05660836_01104	SAMN05660836_01365	Tfp pilus assembly protein PilF.	Glycosyltransferase, GT2 family.	0.975
SFM66643.1	SFM81084.1	SAMN05660836_01104	SAMN05660836_01561	Tfp pilus assembly protein PilF.	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.	0.889
SFM66643.1	SFN05777.1	SAMN05660836_01104	SAMN05660836_02497	Tfp pilus assembly protein PilF.	Cupin domain-containing protein.	0.718
SFM66643.1	SFN07572.1	SAMN05660836_01104	SAMN05660836_02565	Tfp pilus assembly protein PilF.	Mannose-1-phosphate guanylyltransferase.	0.798
SFM66643.1	SFN10948.1	SAMN05660836_01104	SAMN05660836_02686	Tfp pilus assembly protein PilF.	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.	0.889
SFM66643.1	SFN10997.1	SAMN05660836_01104	SAMN05660836_02688	Tfp pilus assembly protein PilF.	Polysaccharide export outer membrane protein.	0.736
SFM66643.1	SFN11022.1	SAMN05660836_01104	SAMN05660836_02689	Tfp pilus assembly protein PilF.	Uncharacterized protein involved in exopolysaccharide biosynthesis.	0.616
SFM66643.1	SFN11064.1	SAMN05660836_01104	SAMN05660836_02691	Tfp pilus assembly protein PilF.	O-antigen ligase.	0.963
SFM74930.1	SFM66643.1	SAMN05660836_01365	SAMN05660836_01104	Glycosyltransferase, GT2 family.	Tfp pilus assembly protein PilF.	0.975
SFM74930.1	SFM81084.1	SAMN05660836_01365	SAMN05660836_01561	Glycosyltransferase, GT2 family.	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.	0.999
SFM74930.1	SFN05777.1	SAMN05660836_01365	SAMN05660836_02497	Glycosyltransferase, GT2 family.	Cupin domain-containing protein.	0.822
SFM74930.1	SFN07572.1	SAMN05660836_01365	SAMN05660836_02565	Glycosyltransferase, GT2 family.	Mannose-1-phosphate guanylyltransferase.	0.872
SFM74930.1	SFN10948.1	SAMN05660836_01365	SAMN05660836_02686	Glycosyltransferase, GT2 family.	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.	0.999
SFM74930.1	SFN10969.1	SAMN05660836_01365	SAMN05660836_02687	Glycosyltransferase, GT2 family.	Sporulation related domain-containing protein.	0.447
SFM74930.1	SFN10997.1	SAMN05660836_01365	SAMN05660836_02688	Glycosyltransferase, GT2 family.	Polysaccharide export outer membrane protein.	0.965
SFM74930.1	SFN11022.1	SAMN05660836_01365	SAMN05660836_02689	Glycosyltransferase, GT2 family.	Uncharacterized protein involved in exopolysaccharide biosynthesis.	0.954
SFM74930.1	SFN11038.1	SAMN05660836_01365	SAMN05660836_02690	Glycosyltransferase, GT2 family.	Chromosome partitioning ATPase, Mrp family, contains Fe-S cluster.	0.833
SFM74930.1	SFN11064.1	SAMN05660836_01365	SAMN05660836_02691	Glycosyltransferase, GT2 family.	O-antigen ligase.	0.848
SFM81084.1	SFM66643.1	SAMN05660836_01561	SAMN05660836_01104	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.	Tfp pilus assembly protein PilF.	0.889
SFM81084.1	SFM74930.1	SAMN05660836_01561	SAMN05660836_01365	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase.	Glycosyltransferase, GT2 family.	0.999

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

40

average node degree:

7.27

avg. local clustering coefficient:

0.896

expected number of edges:

10

PPI enrichment p-value:

9.01e-13

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006177

GMP biosynthetic process

2 of 2

2.75

0.93

0.0232

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0046820

4-amino-4-deoxychorismate synthase activity

2 of 2

2.75

1.06

0.0137

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009317

acetyl-CoA carboxylase complex

2 of 7

2.2

0.84

0.0311

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0332

GMP biosynthesis

2 of 2

2.75

1.38

0.0037

KW-0315

Glutamine amidotransferase

2 of 14

1.9

0.78

0.0365

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00289

Biotin carboxylase, N-terminal domain

2 of 2

2.75

1.08

0.0126

PF04715

Anthranilate synthase component I, N terminal region

2 of 3

2.57

1.07

0.0126

PF02786

Carbamoyl-phosphate synthase L chain, ATP binding domain

2 of 3

2.57

1.07

0.0126

PF00425

Chorismate binding enzyme

2 of 4

2.45

1.07

0.0126

PF07722

Peptidase C26

2 of 5

2.35

1.06

0.0126

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR019999

Anthranilate synthase component I-like

2 of 3

2.57

0.85

0.0318

IPR015890

Chorismate-utilising enzyme, C-terminal

2 of 4

2.45

0.85

0.0318

IPR011764

Biotin carboxylation domain

2 of 2

2.75

0.85

0.0318

IPR011054

Rudiment single hybrid motif

2 of 4

2.45

0.85

0.0318

IPR006805

Anthranilate synthase component I, N-terminal

2 of 3

2.57

0.85

0.0318

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00878

Biotin carboxylase C-terminal domain

2 of 2

2.75

1.47

0.0025

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