| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aceB | citG | BpOF4_01340 | BpOF4_14095 | Malate synthase G part of glyoxylate pathway; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.920 |
| aceB | citZ | BpOF4_01340 | BpOF4_03365 | Malate synthase G part of glyoxylate pathway; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.962 |
| aceB | fumA | BpOF4_01340 | BpOF4_10680 | Malate synthase G part of glyoxylate pathway; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | Fumarate hydratase class I (fumarase); Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.943 |
| aceB | icdA | BpOF4_01340 | BpOF4_03360 | Malate synthase G part of glyoxylate pathway; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | COG0538 Isocitrate dehydrogenases. | 0.549 |
| aceB | mdhA | BpOF4_01340 | BpOF4_03355 | Malate synthase G part of glyoxylate pathway; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.926 |
| aceB | mdhA2 | BpOF4_01340 | BpOF4_12510 | Malate synthase G part of glyoxylate pathway; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | COG0039 Malate/lactate dehydrogenases; Belongs to the LDH/MDH superfamily. | 0.926 |
| aceB | pdhC | BpOF4_01340 | BpOF4_01070 | Malate synthase G part of glyoxylate pathway; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | 0.911 |
| aceB | porA | BpOF4_01340 | BpOF4_19540 | Malate synthase G part of glyoxylate pathway; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | Ferredoxin oxidoreductase,alpha subunit; COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit. | 0.929 |
| bfmBB | citG | BpOF4_01410 | BpOF4_14095 | Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.442 |
| bfmBB | citZ | BpOF4_01410 | BpOF4_03365 | Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.975 |
| bfmBB | fumA | BpOF4_01410 | BpOF4_10680 | Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | Fumarate hydratase class I (fumarase); Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.412 |
| citB | citG | BpOF4_19280 | BpOF4_14095 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.933 |
| citB | citZ | BpOF4_19280 | BpOF4_03365 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.999 |
| citB | fumA | BpOF4_19280 | BpOF4_10680 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Fumarate hydratase class I (fumarase); Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.806 |
| citB | icdA | BpOF4_19280 | BpOF4_03360 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | COG0538 Isocitrate dehydrogenases. | 0.996 |
| citB | mdhA | BpOF4_19280 | BpOF4_03355 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.732 |
| citB | mdhA2 | BpOF4_19280 | BpOF4_12510 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | COG0039 Malate/lactate dehydrogenases; Belongs to the LDH/MDH superfamily. | 0.693 |
| citB | porA | BpOF4_19280 | BpOF4_19540 | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Ferredoxin oxidoreductase,alpha subunit; COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit. | 0.647 |
| citG | aceB | BpOF4_14095 | BpOF4_01340 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Malate synthase G part of glyoxylate pathway; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.920 |
| citG | bfmBB | BpOF4_14095 | BpOF4_01410 | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | 0.442 |