STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADC50664.1COG2208 Serine phosphatase RsbU, regulator of sigma subunit. (282 aa)    
Predicted Functional Partners:
ADC50663.1
Hypothetical protein; COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).
 
 
 0.920
ADC50661.1
Hypothetical protein; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase).
 
 
 0.874
ADC50665.1
COG1847 Predicted RNA-binding protein.
 
     0.842
ADC50666.1
COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
 
     0.819
rsbW
Serine-protein kinase RsbW; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
 
 
 0.789
rsbV
Positive regulator of sigma-B activity; COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
 
   
 0.779
spoIIAA
Anti-sigma F factor antagonist (stage II sporulation protein AA); COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.
 
   
 0.740
ADC50662.1
Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein.
 
  
 0.713
rsbT
Positive regulator of sigma-B activity; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase).
 
 
 0.698
ADC50305.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
  
  
 0.682
Your Current Organism:
Bacillus pseudofirmus
NCBI taxonomy Id: 398511
Other names: B. pseudofirmus OF4, Bacillus pseudofirmus OF4, Bacillus pseudofirmus str. OF4, Bacillus pseudofirmus strain OF4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.