Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Bccel_0222Malonyl CoA-acyl carrier protein transacylase; SMART: Polyketide synthase, acyl transferase domain-containing protein; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; KEGG: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase. (428 aa)    
Predicted Functional Partners:
Bccel_1297
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 0.999
Bccel_1479
6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein.
 
0.998
Bccel_2229
6-deoxyerythronolide-B synthase, 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: Acyl transferase, Beta-ketoacyl synthase, KR domain protein, acyl carrier protein familyprotein; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein.
 
0.998
Bccel_1682
KEGG: thioester reductase; TIGRFAM: thioester reductase domain protein; PFAM: Male sterility domain-containing protein.
 
 0.996
Bccel_0225
6-deoxyerythronolide-B synthase, Phenylalanine racemase (ATP-hydrolyzing); PFAM: Beta-ketoacyl synthase, Uncharacterized protein YobF, acyl carrier protein familyprotein, KR domain protein; KEGG: beta-ketoacyl synthase; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR.
  
 0.986
Bccel_0223
Amino acid adenylation domain protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase, phosphopantetheine-binding protein; TIGRFAM: amino acid adenylation domain protein; KEGG: hybrid nonribosomal peptide synthetase/polyketide synthase; PFAM: AMP-dependent synthetase and ligase, Beta-ketoacyl synthase, acyl carrier protein familyprotein, condensation domain protein.
  
 0.982
fabZ
(3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
 
 0.982
fabH
3-oxoacyl-(acyl-carrier-protein) synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 0.977
Bccel_1693
6-deoxyerythronolide-B synthase, Aspartate racemase; PFAM: condensation domain protein, KR domain protein, Beta-ketoacyl synthase, acyl carrier protein familyprotein; KEGG: putative polyketide synthase component,beta-ketoacyl synthase family protein,phosphopantetheine-containing protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, phosphopantetheine-binding protein.
  
 0.967
Bccel_1482
KEGG: 3-oxoacyl-(acyl-carrier-protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain-containing protein, 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III.
 
 
 0.964
Your Current Organism:
Pseudobacteroides cellulosolvens
NCBI taxonomy Id: 398512
Other names: Bacteroides cellulosolvens ATCC 35603, Bacteroides cellulosolvens DSM 2933, P. cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens DSM 2933 = ATCC 35603
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.