| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bccel_0632 | Bccel_3671 | Bccel_0632 | Bccel_3671 | KEGG: phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SMART: Phosphoglycerate mutase. | KEGG: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein, D-isomer specific 2-hydroxyacid dehydrogenase catalytic region-containing protein. | 0.716 |
| Bccel_0632 | Bccel_3683 | Bccel_0632 | Bccel_3683 | KEGG: phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SMART: Phosphoglycerate mutase. | PBP domain containing protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.730 |
| Bccel_0632 | Bccel_4594 | Bccel_0632 | Bccel_4594 | KEGG: phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SMART: Phosphoglycerate mutase. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.711 |
| Bccel_0632 | cobS | Bccel_0632 | Bccel_2107 | KEGG: phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SMART: Phosphoglycerate mutase. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.854 |
| Bccel_0632 | cobS-2 | Bccel_0632 | Bccel_3264 | KEGG: phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SMART: Phosphoglycerate mutase. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.853 |
| Bccel_0632 | cobT | Bccel_0632 | Bccel_1774 | KEGG: phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SMART: Phosphoglycerate mutase. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.751 |
| Bccel_0632 | cobT-2 | Bccel_0632 | Bccel_3246 | KEGG: phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SMART: Phosphoglycerate mutase. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.752 |
| Bccel_0632 | eno | Bccel_0632 | Bccel_3750 | KEGG: phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SMART: Phosphoglycerate mutase. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.711 |
| Bccel_0632 | glyA | Bccel_0632 | Bccel_1518 | KEGG: phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SMART: Phosphoglycerate mutase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.717 |
| Bccel_0632 | pgk | Bccel_0632 | Bccel_3754 | KEGG: phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SMART: Phosphoglycerate mutase. | HAMAP : Phosphoglycerate kinase; KEGG: 3-phosphoglycerate kinase; PFAM: phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.738 |
| Bccel_3671 | Bccel_0632 | Bccel_3671 | Bccel_0632 | KEGG: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein, D-isomer specific 2-hydroxyacid dehydrogenase catalytic region-containing protein. | KEGG: phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SMART: Phosphoglycerate mutase. | 0.716 |
| Bccel_3671 | Bccel_4594 | Bccel_3671 | Bccel_4594 | KEGG: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein, D-isomer specific 2-hydroxyacid dehydrogenase catalytic region-containing protein. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.999 |
| Bccel_3671 | eno | Bccel_3671 | Bccel_3750 | KEGG: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein, D-isomer specific 2-hydroxyacid dehydrogenase catalytic region-containing protein. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.539 |
| Bccel_3671 | glyA | Bccel_3671 | Bccel_1518 | KEGG: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein, D-isomer specific 2-hydroxyacid dehydrogenase catalytic region-containing protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.583 |
| Bccel_3683 | Bccel_0632 | Bccel_3683 | Bccel_0632 | PBP domain containing protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | KEGG: phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SMART: Phosphoglycerate mutase. | 0.730 |
| Bccel_4594 | Bccel_0632 | Bccel_4594 | Bccel_0632 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | KEGG: phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SMART: Phosphoglycerate mutase. | 0.711 |
| Bccel_4594 | Bccel_3671 | Bccel_4594 | Bccel_3671 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | KEGG: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein, D-isomer specific 2-hydroxyacid dehydrogenase catalytic region-containing protein. | 0.999 |
| Bccel_4594 | glyA | Bccel_4594 | Bccel_1518 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.817 |
| cobS | Bccel_0632 | Bccel_2107 | Bccel_0632 | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | KEGG: phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SMART: Phosphoglycerate mutase. | 0.854 |
| cobS | cobT | Bccel_2107 | Bccel_1774 | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.886 |