Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (281 aa)    
Predicted Functional Partners:
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
 
 0.999
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
 0.999
Bccel_2252
PFAM: Domain of unknown function DUF2520-containing protein, oxidoreductase/dehydrogenase, Rossmann-like domain-containing protein; KEGG: NADP oxidoreductase, coenzyme F420-dependent.
  
 0.990
coaX
Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
  
 
 0.970
cmk
TIGRFAM: cytidylate kinase; HAMAP : Cytidylate kinase; KEGG: cytidylate kinase; PFAM: cytidylate kinase region.
   
  0.960
Bccel_2052
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
  
 0.889
birA
BirA bifunctional protein, biotin operon repressor and biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
 
 0.857
Bccel_2291
KEGG: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; SMART: AAA ATPase.
  
  0.831
Bccel_0979
Acetaldehyde dehydrogenase (acetylating); KEGG: alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase, Aldehyde Dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
    
 0.813
Bccel_1987
PFAM: metallophosphoesterase; KEGG: UshA protein; Belongs to the 5'-nucleotidase family.
    
  0.799
Your Current Organism:
Pseudobacteroides cellulosolvens
NCBI taxonomy Id: 398512
Other names: Bacteroides cellulosolvens ATCC 35603, Bacteroides cellulosolvens DSM 2933, P. cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens DSM 2933 = ATCC 35603
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