Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Bccel_0782KEGG: adenosine deaminase; PFAM: adenosine/AMP deaminase. (318 aa)    
Predicted Functional Partners:
Bccel_2596
Purine operon repressor, PurR; KEGG: pur operon repressor; TIGRFAM: pur operon repressor; PFAM: purine repressor, phosphoribosyltransferase.
   
 0.926
Bccel_3505
Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.912
Bccel_1565
KEGG: IMP dehydrogenase/GMP reductase; PFAM: IMP dehydrogenase/GMP reductase, CBS domain containing protein.
  
 0.853
Bccel_3503
KEGG: ribokinase-like domain-containing protein; PFAM: PfkB domain protein.
    
 0.840
Bccel_5704
PFAM: Domain of unknown function DUF3706; KEGG: hypothetical protein.
   
 0.827
Bccel_1727
KEGG: hypothetical protein; TIGRFAM: Multi-copper polyphenol oxidoreductase, laccase; PFAM: Multi-copper polyphenol oxidoreductase, laccase; Belongs to the multicopper oxidase YfiH/RL5 family.
    
 0.772
ppnP
UPF0345 protein yaiE; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
 0.771
Bccel_3911
TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.771
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.718
Bccel_1987
PFAM: metallophosphoesterase; KEGG: UshA protein; Belongs to the 5'-nucleotidase family.
    
 0.714
Your Current Organism:
Pseudobacteroides cellulosolvens
NCBI taxonomy Id: 398512
Other names: Bacteroides cellulosolvens ATCC 35603, Bacteroides cellulosolvens DSM 2933, P. cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens DSM 2933 = ATCC 35603
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