STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bccel_1243Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (317 aa)    
Predicted Functional Partners:
proS
Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
  
 
 0.758
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
 
 
 0.653
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
    0.592
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
  
 
 0.584
glnS
PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain-containing protein, Glutamyl/glutaminyl-tRNA synthetase, class Ic, anti-codon binding domain-containing protein; TIGRFAM: glutaminyl-tRNA synthetase; HAMAP : Glutaminyl-tRNA synthetase; KEGG: glutaminyl-tRNA synthetase.
  
 
 0.581
Bccel_1244
PFAM: Leucine rich repeat 5; KEGG: leucine rich repeats containing protein.
       0.580
Bccel_1245
PFAM: NADP-dependent oxidoreductase domain; KEGG: aldo/keto reductase.
       0.568
Bccel_1479
6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein.
  
 
 0.547
Bccel_2229
6-deoxyerythronolide-B synthase, 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: Acyl transferase, Beta-ketoacyl synthase, KR domain protein, acyl carrier protein familyprotein; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein.
  
 
 0.547
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.546
Your Current Organism:
Pseudobacteroides cellulosolvens
NCBI taxonomy Id: 398512
Other names: Bacteroides cellulosolvens ATCC 35603, Bacteroides cellulosolvens DSM 2933, P. cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens DSM 2933 = ATCC 35603
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.