STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
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[Homology]
Score
iscSCysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (396 aa)    
Predicted Functional Partners:
Bccel_1513
KEGG: FeS cluster assembly scaffold protein NifU; TIGRFAM: FeS cluster assembly scaffold protein NifU; PFAM: nitrogen-fixing NifU domain protein.
 
 0.999
Bccel_4743
PFAM: nitrogen-fixing NifU domain protein; KEGG: hypothetical protein.
 
 0.997
Bccel_1515
KEGG: rrf2 family protein, putative transcriptional regulator; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074.
 
 0.992
Bccel_1449
CoA-disulfide reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain, pyridine nucleotide-disulfide oxidoreductase dimerization region, SirA-like domain-containing protein, Rhodanese-like protein, FAD-dependent pyridine nucleotide-disulfide oxidoreductase; KEGG: NAD(FAD)-dependent dehydrogenase; SMART: Rhodanese-like protein; Belongs to the sulfur carrier protein TusA family.
   
 0.991
Bccel_5434
Hypothetical protein; KEGG: NifU-like domain-containing protein.
  
 0.988
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
   
 0.947
thiI
tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
 0.945
Bccel_5260
PFAM: UBA/THIF-type NAD/FAD binding protein, MoeZ/MoeB domain protein; KEGG: UBA/THIF-type NAD/FAD binding protein.
   
 0.934
Bccel_5197
KEGG: SirA-like protein; TIGRFAM: selenium metabolism protein YedF; PFAM: DsrE family protein.
   
 0.914
Bccel_1013
KEGG: cysteine desulfurase; PFAM: aminotransferase class V.
  
  
 
0.903
Your Current Organism:
Pseudobacteroides cellulosolvens
NCBI taxonomy Id: 398512
Other names: Bacteroides cellulosolvens ATCC 35603, Bacteroides cellulosolvens DSM 2933, P. cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens DSM 2933 = ATCC 35603
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