node1 | node2 | node1 annotation | node2 annotation | score |
Bccel_1479 | Bccel_1504 | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.726 |
Bccel_1479 | Bccel_1878 | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | PFAM: protein of unknown function DUF894 DitE; KEGG: major facilitator superfamily protein. | 0.555 |
Bccel_1479 | Bccel_2229 | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | 6-deoxyerythronolide-B synthase, 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: Acyl transferase, Beta-ketoacyl synthase, KR domain protein, acyl carrier protein familyprotein; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | 0.999 |
Bccel_1479 | Bccel_5564 | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | Methionine synthase; PFAM: homocysteine S-methyltransferase, cobalamin B12-binding domain protein, Methionine synthase B12-binding module cap domain protein, dihydropteroate synthase DHPS; KEGG: homocysteine S-methyltransferase; SMART: Methionine synthase B12-binding module cap domain protein. | 0.726 |
Bccel_1504 | Bccel_1479 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | 0.726 |
Bccel_1504 | Bccel_1878 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: protein of unknown function DUF894 DitE; KEGG: major facilitator superfamily protein. | 0.627 |
Bccel_1504 | Bccel_2229 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 6-deoxyerythronolide-B synthase, 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: Acyl transferase, Beta-ketoacyl synthase, KR domain protein, acyl carrier protein familyprotein; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | 0.726 |
Bccel_1504 | Bccel_3515 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: homoserine dehydrogenase, homoserine dehydrogenase NAD-binding protein; KEGG: homoserine dehydrogenase. | 0.924 |
Bccel_1504 | Bccel_3936 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: homoserine dehydrogenase, homoserine dehydrogenase NAD-binding protein; KEGG: homoserine dehydrogenase. | 0.924 |
Bccel_1504 | Bccel_5564 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine synthase; PFAM: homocysteine S-methyltransferase, cobalamin B12-binding domain protein, Methionine synthase B12-binding module cap domain protein, dihydropteroate synthase DHPS; KEGG: homocysteine S-methyltransferase; SMART: Methionine synthase B12-binding module cap domain protein. | 0.969 |
Bccel_1878 | Bccel_1479 | PFAM: protein of unknown function DUF894 DitE; KEGG: major facilitator superfamily protein. | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | 0.555 |
Bccel_1878 | Bccel_1504 | PFAM: protein of unknown function DUF894 DitE; KEGG: major facilitator superfamily protein. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.627 |
Bccel_1878 | Bccel_1879 | PFAM: protein of unknown function DUF894 DitE; KEGG: major facilitator superfamily protein. | PFAM: protein of unknown function DUF6 transmembrane; KEGG: transporter, EamA-like family. | 0.520 |
Bccel_1878 | Bccel_2229 | PFAM: protein of unknown function DUF894 DitE; KEGG: major facilitator superfamily protein. | 6-deoxyerythronolide-B synthase, 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: Acyl transferase, Beta-ketoacyl synthase, KR domain protein, acyl carrier protein familyprotein; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | 0.555 |
Bccel_1878 | Bccel_3515 | PFAM: protein of unknown function DUF894 DitE; KEGG: major facilitator superfamily protein. | PFAM: homoserine dehydrogenase, homoserine dehydrogenase NAD-binding protein; KEGG: homoserine dehydrogenase. | 0.452 |
Bccel_1878 | Bccel_3557 | PFAM: protein of unknown function DUF894 DitE; KEGG: major facilitator superfamily protein. | Hypothetical protein; KEGG: alpha/beta hydrolase. | 0.504 |
Bccel_1878 | Bccel_3802 | PFAM: protein of unknown function DUF894 DitE; KEGG: major facilitator superfamily protein. | PFAM: Protein of unknown function DUF2089; KEGG: hypothetical protein. | 0.465 |
Bccel_1878 | Bccel_3936 | PFAM: protein of unknown function DUF894 DitE; KEGG: major facilitator superfamily protein. | PFAM: homoserine dehydrogenase, homoserine dehydrogenase NAD-binding protein; KEGG: homoserine dehydrogenase. | 0.452 |
Bccel_1878 | Bccel_4735 | PFAM: protein of unknown function DUF894 DitE; KEGG: major facilitator superfamily protein. | Phosphonate-transporting ATPase; PFAM: ABC transporter related protein; KEGG: ABC transporter; SMART: AAA ATPase. | 0.511 |
Bccel_1878 | Bccel_5564 | PFAM: protein of unknown function DUF894 DitE; KEGG: major facilitator superfamily protein. | Methionine synthase; PFAM: homocysteine S-methyltransferase, cobalamin B12-binding domain protein, Methionine synthase B12-binding module cap domain protein, dihydropteroate synthase DHPS; KEGG: homocysteine S-methyltransferase; SMART: Methionine synthase B12-binding module cap domain protein. | 0.627 |