| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bccel_0537 | Bccel_1479 | Bccel_0537 | Bccel_1479 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; KEGG: anthranilate synthase, component II; PFAM: Glutamine amidotransferase type 1. | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | 0.486 |
| Bccel_0537 | Bccel_1983 | Bccel_0537 | Bccel_1983 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; KEGG: anthranilate synthase, component II; PFAM: Glutamine amidotransferase type 1. | TIGRFAM: branched-chain amino acid aminotransferase; KEGG: branched-chain amino acid aminotransferase, group II; PFAM: aminotransferase class IV. | 0.873 |
| Bccel_0537 | Bccel_2229 | Bccel_0537 | Bccel_2229 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; KEGG: anthranilate synthase, component II; PFAM: Glutamine amidotransferase type 1. | 6-deoxyerythronolide-B synthase, 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: Acyl transferase, Beta-ketoacyl synthase, KR domain protein, acyl carrier protein familyprotein; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | 0.486 |
| Bccel_0537 | Bccel_2690 | Bccel_0537 | Bccel_2690 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; KEGG: anthranilate synthase, component II; PFAM: Glutamine amidotransferase type 1. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.780 |
| Bccel_0537 | Bccel_3959 | Bccel_0537 | Bccel_3959 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; KEGG: anthranilate synthase, component II; PFAM: Glutamine amidotransferase type 1. | SMART: Chorismate mutase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; PFAM: DAHP synthetase I/KDSA, Chorismate mutase, type II. | 0.918 |
| Bccel_1479 | Bccel_0537 | Bccel_1479 | Bccel_0537 | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | TIGRFAM: glutamine amidotransferase of anthranilate synthase; KEGG: anthranilate synthase, component II; PFAM: Glutamine amidotransferase type 1. | 0.486 |
| Bccel_1479 | Bccel_1567 | Bccel_1479 | Bccel_1567 | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein, thiamine pyrophosphate TPP-binding domain-containing protein, Pyruvate/ketoisovalerate oxidoreductase, Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein. | 0.944 |
| Bccel_1479 | Bccel_1983 | Bccel_1479 | Bccel_1983 | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | TIGRFAM: branched-chain amino acid aminotransferase; KEGG: branched-chain amino acid aminotransferase, group II; PFAM: aminotransferase class IV. | 0.936 |
| Bccel_1479 | Bccel_2229 | Bccel_1479 | Bccel_2229 | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | 6-deoxyerythronolide-B synthase, 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: Acyl transferase, Beta-ketoacyl synthase, KR domain protein, acyl carrier protein familyprotein; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | 0.999 |
| Bccel_1479 | Bccel_2690 | Bccel_1479 | Bccel_2690 | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.481 |
| Bccel_1479 | Bccel_3831 | Bccel_1479 | Bccel_3831 | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, Pyruvate/ketoisovalerate oxidoreductase, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein, Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein, Transketolase domain-containing protein, thiamine pyrophosphate TPP-binding domain-containing protein. | 0.951 |
| Bccel_1479 | Bccel_3959 | Bccel_1479 | Bccel_3959 | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | SMART: Chorismate mutase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; PFAM: DAHP synthetase I/KDSA, Chorismate mutase, type II. | 0.576 |
| Bccel_1479 | ilvD | Bccel_1479 | Bccel_4415 | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; TIGRFAM: dihydroxy-acid dehydratase; HAMAP : Dihydroxy-acid dehydratase; KEGG: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.648 |
| Bccel_1479 | leuA | Bccel_1479 | Bccel_4551 | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.855 |
| Bccel_1567 | Bccel_1479 | Bccel_1567 | Bccel_1479 | SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein, thiamine pyrophosphate TPP-binding domain-containing protein, Pyruvate/ketoisovalerate oxidoreductase, Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein. | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | 0.944 |
| Bccel_1567 | Bccel_1983 | Bccel_1567 | Bccel_1983 | SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein, thiamine pyrophosphate TPP-binding domain-containing protein, Pyruvate/ketoisovalerate oxidoreductase, Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein. | TIGRFAM: branched-chain amino acid aminotransferase; KEGG: branched-chain amino acid aminotransferase, group II; PFAM: aminotransferase class IV. | 0.872 |
| Bccel_1567 | Bccel_2229 | Bccel_1567 | Bccel_2229 | SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein, thiamine pyrophosphate TPP-binding domain-containing protein, Pyruvate/ketoisovalerate oxidoreductase, Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein. | 6-deoxyerythronolide-B synthase, 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: Acyl transferase, Beta-ketoacyl synthase, KR domain protein, acyl carrier protein familyprotein; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | 0.944 |
| Bccel_1567 | Bccel_3831 | Bccel_1567 | Bccel_3831 | SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein, thiamine pyrophosphate TPP-binding domain-containing protein, Pyruvate/ketoisovalerate oxidoreductase, Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein. | SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, Pyruvate/ketoisovalerate oxidoreductase, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein, Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein, Transketolase domain-containing protein, thiamine pyrophosphate TPP-binding domain-containing protein. | 0.999 |
| Bccel_1567 | Bccel_3959 | Bccel_1567 | Bccel_3959 | SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein, thiamine pyrophosphate TPP-binding domain-containing protein, Pyruvate/ketoisovalerate oxidoreductase, Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein. | SMART: Chorismate mutase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; PFAM: DAHP synthetase I/KDSA, Chorismate mutase, type II. | 0.804 |
| Bccel_1567 | leuA | Bccel_1567 | Bccel_4551 | SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein, thiamine pyrophosphate TPP-binding domain-containing protein, Pyruvate/ketoisovalerate oxidoreductase, Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.889 |