Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Bccel_1987PFAM: metallophosphoesterase; KEGG: UshA protein; Belongs to the 5'-nucleotidase family. (368 aa)    
Predicted Functional Partners:
Bccel_1565
KEGG: IMP dehydrogenase/GMP reductase; PFAM: IMP dehydrogenase/GMP reductase, CBS domain containing protein.
   
 0.858
cinA
Competence-damaged protein; SMART: molybdopterin binding domain-containing protein; TIGRFAM: competence/damage-inducible protein CinA, CinA domain protein, molybdenum cofactor synthesis domain protein; KEGG: competence/damage-inducible protein CinA; HAMAP : Competence-damaged protein; PFAM: CinA domain protein, molybdopterin binding domain-containing protein.
  
 
  0.850
Bccel_2291
KEGG: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; SMART: AAA ATPase.
  
 
 0.834
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
 0.809
Bccel_3316
Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
    
 0.807
Bccel_0426
KEGG: cytidyltransferase-related domain-containing protein; TIGRFAM: cytidyltransferase-related domain protein; PFAM: Citrate lyase ligase domain protein.
     
 0.803
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
    
  0.799
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
    
 0.789
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
 0.785
Bccel_0999
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
 
  
 0.780
Your Current Organism:
Pseudobacteroides cellulosolvens
NCBI taxonomy Id: 398512
Other names: Bacteroides cellulosolvens ATCC 35603, Bacteroides cellulosolvens DSM 2933, P. cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens DSM 2933 = ATCC 35603
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