Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Bccel_2019TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. (425 aa)    
Predicted Functional Partners:
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
 
 
 0.955
Bccel_1504
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.953
Bccel_5564
Methionine synthase; PFAM: homocysteine S-methyltransferase, cobalamin B12-binding domain protein, Methionine synthase B12-binding module cap domain protein, dihydropteroate synthase DHPS; KEGG: homocysteine S-methyltransferase; SMART: Methionine synthase B12-binding module cap domain protein.
  
 
 0.953
Bccel_3515
PFAM: homoserine dehydrogenase, homoserine dehydrogenase NAD-binding protein; KEGG: homoserine dehydrogenase.
 
 
 0.885
Bccel_1709
PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: Cys/Met metabolism pyridoxal-phosphate-dependent protein.
 
 
0.848
Bccel_1708
PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: cystathionine gamma-synthase.
 
 
0.843
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.838
Bccel_1449
CoA-disulfide reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain, pyridine nucleotide-disulfide oxidoreductase dimerization region, SirA-like domain-containing protein, Rhodanese-like protein, FAD-dependent pyridine nucleotide-disulfide oxidoreductase; KEGG: NAD(FAD)-dependent dehydrogenase; SMART: Rhodanese-like protein; Belongs to the sulfur carrier protein TusA family.
    
 0.831
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
 0.821
Bccel_3936
PFAM: homoserine dehydrogenase, homoserine dehydrogenase NAD-binding protein; KEGG: homoserine dehydrogenase.
 
 
 0.794
Your Current Organism:
Pseudobacteroides cellulosolvens
NCBI taxonomy Id: 398512
Other names: Bacteroides cellulosolvens ATCC 35603, Bacteroides cellulosolvens DSM 2933, P. cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens DSM 2933 = ATCC 35603
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