STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bccel_2023Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. (266 aa)    
Predicted Functional Partners:
Bccel_2024
TIGRFAM: stage IV sporulation protein B; KEGG: stage IV sporulation protein B; PFAM: peptidase S55 SpoIVB.
   
 0.936
Bccel_1876
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.849
Bccel_1736
RNA polymerase, sigma 28 subunit, SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.844
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
  
 0.835
Bccel_5640
KEGG: stage II sporulation protein R; TIGRFAM: stage II sporulation protein R; PFAM: Sporulation stage II protein R.
  
   
 0.835
Bccel_1735
RNA polymerase, sigma 28 subunit, SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.833
Bccel_2589
TIGRFAM: stage V sporulation protein T, transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain-containing protein; KEGG: stage V sporulation protein T; SMART: SpoVT/AbrB domain-containing protein.
  
   
 0.833
Bccel_3861
KEGG: stage V sporulation protein AD; TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein.
  
   
 0.833
gpr
Germination protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
   
 0.828
Bccel_5501
KEGG: sporulation transcriptional regulator SpoIIID; TIGRFAM: sporulation transcriptional regulator SpoIIID; PFAM: Sporulation stage III transcriptional regulator SpoIIID.
  
   
 0.828
Your Current Organism:
Pseudobacteroides cellulosolvens
NCBI taxonomy Id: 398512
Other names: Bacteroides cellulosolvens ATCC 35603, Bacteroides cellulosolvens DSM 2933, P. cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens DSM 2933 = ATCC 35603
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