Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
guaAGMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (511 aa)    
Predicted Functional Partners:
Bccel_1565
KEGG: IMP dehydrogenase/GMP reductase; PFAM: IMP dehydrogenase/GMP reductase, CBS domain containing protein.
 0.999
Bccel_3705
TIGRFAM: phosphoribosylformylglycinamidine synthase; KEGG: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein, AIR synthase related protein.
  
  
 0.981
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
 
 
 0.973
Bccel_2596
Purine operon repressor, PurR; KEGG: pur operon repressor; TIGRFAM: pur operon repressor; PFAM: purine repressor, phosphoribosyltransferase.
  
 0.969
Bccel_2437
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
 
 0.968
rpsM
Ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.
  
 
 0.967
Bccel_5704
PFAM: Domain of unknown function DUF3706; KEGG: hypothetical protein.
  
 0.963
argS
KEGG: argS, arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; HAMAP : Arginyl-tRNA synthetase.
 
  
 0.961
rplK
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
    0.961
Bccel_2389
Nucleoside-triphosphatase rdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
 
 0.956
Your Current Organism:
Pseudobacteroides cellulosolvens
NCBI taxonomy Id: 398512
Other names: Bacteroides cellulosolvens ATCC 35603, Bacteroides cellulosolvens DSM 2933, P. cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens DSM 2933 = ATCC 35603
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