Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Bccel_2249KEGG: hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP01212; SMART: Elongator protein 3/MiaB/NifB. (317 aa)    
Predicted Functional Partners:
Bccel_0623
PFAM: rRNA methylase; KEGG: rRNA methylase; overlaps another CDS with the same product name.
 
    0.789
larC
UPF0272 protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
       0.787
Bccel_2251
KEGG: NCAIR mutase-like protein; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; SMART: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase.
       0.749
Bccel_2252
PFAM: Domain of unknown function DUF2520-containing protein, oxidoreductase/dehydrogenase, Rossmann-like domain-containing protein; KEGG: NADP oxidoreductase, coenzyme F420-dependent.
       0.741
Bccel_1958
KEGG: radical SAM protein; PFAM: cobalamin B12-binding domain protein, Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.
    
 0.713
prfB
Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
       0.689
Bccel_0624
PFAM: rRNA methylase; KEGG: rRNA methylase; overlaps another CDS with the same product name.
 
    0.684
Bccel_3810
KEGG: AraC family transcriptional regulator; PFAM: transcription activator effector binding protein; SMART: transcription activator effector binding protein.
   
    0.590
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
 
     0.531
Bccel_2111
TIGRFAM: Hypoxanthine-DNA glycosylase; PFAM: Uracil-DNA glycosylase superfamily; KEGG: G:T/U mismatch-specific DNA glycosylase; SMART: Uracil-DNA glycosylase superfamily.
 
      0.468
Your Current Organism:
Pseudobacteroides cellulosolvens
NCBI taxonomy Id: 398512
Other names: Bacteroides cellulosolvens ATCC 35603, Bacteroides cellulosolvens DSM 2933, P. cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens DSM 2933 = ATCC 35603
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