STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
larCUPF0272 protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. (466 aa)    
Predicted Functional Partners:
Bccel_1872
KEGG: hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP00268; PFAM: asparagine synthase.
  
 0.989
Bccel_2251
KEGG: NCAIR mutase-like protein; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; SMART: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase.
 
  
 0.987
Bccel_2249
KEGG: hypothetical protein; TIGRFAM: Conserved hypothetical protein CHP01212; SMART: Elongator protein 3/MiaB/NifB.
       0.782
Bccel_2252
PFAM: Domain of unknown function DUF2520-containing protein, oxidoreductase/dehydrogenase, Rossmann-like domain-containing protein; KEGG: NADP oxidoreductase, coenzyme F420-dependent.
       0.741
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
 
      0.695
prfB
Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
       0.689
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
       0.638
Bccel_4577
KEGG: cobalt ABC transporter permease; TIGRFAM: cobalt ABC transporter, inner membrane subunit CbiQ; PFAM: ABC-type transporter, integral membrane subunit.
  
    0.574
cbiM
Cobalamin biosynthesis protein CbiM-like protein; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
    0.519
Bccel_4578
PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein, PDGLE domain; KEGG: cobalamin (vitamin B12) biosynthesis CbiM protein.
  
    0.519
Your Current Organism:
Pseudobacteroides cellulosolvens
NCBI taxonomy Id: 398512
Other names: Bacteroides cellulosolvens ATCC 35603, Bacteroides cellulosolvens DSM 2933, P. cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens DSM 2933 = ATCC 35603
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