STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bccel_2805(R)-citramalate synthase; PFAM: pyruvate carboxyltransferase, LeuA allosteric (dimerization) domain-containing protein; KEGG: leuA2, 2-isopropylmalate synthase LeuA; SMART: LeuA allosteric (dimerization) domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (504 aa)    
Predicted Functional Partners:
Bccel_1389
PFAM: aconitate hydratase domain-containing protein; KEGG: 3-isopropylmalate dehydratase small subunit; Belongs to the LeuD family.
 
 
 0.974
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 0.972
ilvD
PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; TIGRFAM: dihydroxy-acid dehydratase; HAMAP : Dihydroxy-acid dehydratase; KEGG: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.949
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 0.921
Bccel_3831
SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, Pyruvate/ketoisovalerate oxidoreductase, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein, Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein, Transketolase domain-containing protein, thiamine pyrophosphate TPP-binding domain-containing protein.
  
 
 0.903
Bccel_1567
SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein, 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein, thiamine pyrophosphate TPP-binding domain-containing protein, Pyruvate/ketoisovalerate oxidoreductase, Pyruvate-flavodoxin oxidoreductase, EKR domain-containing protein.
  
 
 0.889
Bccel_4414
TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; KEGG: acetolactate synthase, large subunit; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein, thiamine pyrophosphate central domain-containing protein.
 
 
 0.884
Bccel_4553
KEGG: acetolactate synthase small subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit.
  
 
 0.877
Bccel_1983
TIGRFAM: branched-chain amino acid aminotransferase; KEGG: branched-chain amino acid aminotransferase, group II; PFAM: aminotransferase class IV.
  
 0.865
Bccel_1479
6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein.
  
 
 0.855
Your Current Organism:
Pseudobacteroides cellulosolvens
NCBI taxonomy Id: 398512
Other names: Bacteroides cellulosolvens ATCC 35603, Bacteroides cellulosolvens DSM 2933, P. cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens DSM 2933 = ATCC 35603
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