| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bccel_0448 | Bccel_0451 | Bccel_0448 | Bccel_0451 | PFAM: RNA ligase, T4 RnlA-like protein; KEGG: aldehyde dehydrogenase. | TIGRFAM: Polynucleotide kinase-phosphatase, bacterial; KEGG: polynucleotide 3'-phosphatase,polynucleotide 5'-hydroxyl-kinase,polynucleotide 2',3'-cyclic phosphate phosphodiesterase; PFAM: metallophosphoesterase. | 0.658 |
| Bccel_0448 | Bccel_3388 | Bccel_0448 | Bccel_3388 | PFAM: RNA ligase, T4 RnlA-like protein; KEGG: aldehyde dehydrogenase. | KEGG: methyltransferase family protein. | 0.614 |
| Bccel_0451 | Bccel_0448 | Bccel_0451 | Bccel_0448 | TIGRFAM: Polynucleotide kinase-phosphatase, bacterial; KEGG: polynucleotide 3'-phosphatase,polynucleotide 5'-hydroxyl-kinase,polynucleotide 2',3'-cyclic phosphate phosphodiesterase; PFAM: metallophosphoesterase. | PFAM: RNA ligase, T4 RnlA-like protein; KEGG: aldehyde dehydrogenase. | 0.658 |
| Bccel_0451 | Bccel_3388 | Bccel_0451 | Bccel_3388 | TIGRFAM: Polynucleotide kinase-phosphatase, bacterial; KEGG: polynucleotide 3'-phosphatase,polynucleotide 5'-hydroxyl-kinase,polynucleotide 2',3'-cyclic phosphate phosphodiesterase; PFAM: metallophosphoesterase. | KEGG: methyltransferase family protein. | 0.681 |
| Bccel_0451 | Bccel_4459 | Bccel_0451 | Bccel_4459 | TIGRFAM: Polynucleotide kinase-phosphatase, bacterial; KEGG: polynucleotide 3'-phosphatase,polynucleotide 5'-hydroxyl-kinase,polynucleotide 2',3'-cyclic phosphate phosphodiesterase; PFAM: metallophosphoesterase. | PFAM: metal-dependent phosphohydrolase HD sub domain-containing protein; KEGG: metal dependent phosphohydrolase. | 0.559 |
| Bccel_1219 | Bccel_1449 | Bccel_1219 | Bccel_1449 | PFAM: Rieske [2Fe-2S] iron-sulfur domain-containing protein; KEGG: glycine/D-amino acid oxidase, deaminating. | CoA-disulfide reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain, pyridine nucleotide-disulfide oxidoreductase dimerization region, SirA-like domain-containing protein, Rhodanese-like protein, FAD-dependent pyridine nucleotide-disulfide oxidoreductase; KEGG: NAD(FAD)-dependent dehydrogenase; SMART: Rhodanese-like protein; Belongs to the sulfur carrier protein TusA family. | 0.952 |
| Bccel_1219 | Bccel_1479 | Bccel_1219 | Bccel_1479 | PFAM: Rieske [2Fe-2S] iron-sulfur domain-containing protein; KEGG: glycine/D-amino acid oxidase, deaminating. | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | 0.959 |
| Bccel_1219 | Bccel_2229 | Bccel_1219 | Bccel_2229 | PFAM: Rieske [2Fe-2S] iron-sulfur domain-containing protein; KEGG: glycine/D-amino acid oxidase, deaminating. | 6-deoxyerythronolide-B synthase, 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: Acyl transferase, Beta-ketoacyl synthase, KR domain protein, acyl carrier protein familyprotein; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | 0.959 |
| Bccel_1219 | Bccel_3070 | Bccel_1219 | Bccel_3070 | PFAM: Rieske [2Fe-2S] iron-sulfur domain-containing protein; KEGG: glycine/D-amino acid oxidase, deaminating. | PFAM: Uncharacterized protein family UPF0311; KEGG: cellulosome protein dockerin type I. | 0.879 |
| Bccel_1219 | Bccel_3388 | Bccel_1219 | Bccel_3388 | PFAM: Rieske [2Fe-2S] iron-sulfur domain-containing protein; KEGG: glycine/D-amino acid oxidase, deaminating. | KEGG: methyltransferase family protein. | 0.651 |
| Bccel_1219 | glyA | Bccel_1219 | Bccel_1518 | PFAM: Rieske [2Fe-2S] iron-sulfur domain-containing protein; KEGG: glycine/D-amino acid oxidase, deaminating. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.809 |
| Bccel_1449 | Bccel_1219 | Bccel_1449 | Bccel_1219 | CoA-disulfide reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain, pyridine nucleotide-disulfide oxidoreductase dimerization region, SirA-like domain-containing protein, Rhodanese-like protein, FAD-dependent pyridine nucleotide-disulfide oxidoreductase; KEGG: NAD(FAD)-dependent dehydrogenase; SMART: Rhodanese-like protein; Belongs to the sulfur carrier protein TusA family. | PFAM: Rieske [2Fe-2S] iron-sulfur domain-containing protein; KEGG: glycine/D-amino acid oxidase, deaminating. | 0.952 |
| Bccel_1449 | Bccel_1479 | Bccel_1449 | Bccel_1479 | CoA-disulfide reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain, pyridine nucleotide-disulfide oxidoreductase dimerization region, SirA-like domain-containing protein, Rhodanese-like protein, FAD-dependent pyridine nucleotide-disulfide oxidoreductase; KEGG: NAD(FAD)-dependent dehydrogenase; SMART: Rhodanese-like protein; Belongs to the sulfur carrier protein TusA family. | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | 0.936 |
| Bccel_1449 | Bccel_2229 | Bccel_1449 | Bccel_2229 | CoA-disulfide reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain, pyridine nucleotide-disulfide oxidoreductase dimerization region, SirA-like domain-containing protein, Rhodanese-like protein, FAD-dependent pyridine nucleotide-disulfide oxidoreductase; KEGG: NAD(FAD)-dependent dehydrogenase; SMART: Rhodanese-like protein; Belongs to the sulfur carrier protein TusA family. | 6-deoxyerythronolide-B synthase, 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: Acyl transferase, Beta-ketoacyl synthase, KR domain protein, acyl carrier protein familyprotein; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | 0.936 |
| Bccel_1449 | Bccel_3388 | Bccel_1449 | Bccel_3388 | CoA-disulfide reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain, pyridine nucleotide-disulfide oxidoreductase dimerization region, SirA-like domain-containing protein, Rhodanese-like protein, FAD-dependent pyridine nucleotide-disulfide oxidoreductase; KEGG: NAD(FAD)-dependent dehydrogenase; SMART: Rhodanese-like protein; Belongs to the sulfur carrier protein TusA family. | KEGG: methyltransferase family protein. | 0.619 |
| Bccel_1449 | glyA | Bccel_1449 | Bccel_1518 | CoA-disulfide reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain, pyridine nucleotide-disulfide oxidoreductase dimerization region, SirA-like domain-containing protein, Rhodanese-like protein, FAD-dependent pyridine nucleotide-disulfide oxidoreductase; KEGG: NAD(FAD)-dependent dehydrogenase; SMART: Rhodanese-like protein; Belongs to the sulfur carrier protein TusA family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.884 |
| Bccel_1479 | Bccel_1219 | Bccel_1479 | Bccel_1219 | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | PFAM: Rieske [2Fe-2S] iron-sulfur domain-containing protein; KEGG: glycine/D-amino acid oxidase, deaminating. | 0.959 |
| Bccel_1479 | Bccel_1449 | Bccel_1479 | Bccel_1449 | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | CoA-disulfide reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain, pyridine nucleotide-disulfide oxidoreductase dimerization region, SirA-like domain-containing protein, Rhodanese-like protein, FAD-dependent pyridine nucleotide-disulfide oxidoreductase; KEGG: NAD(FAD)-dependent dehydrogenase; SMART: Rhodanese-like protein; Belongs to the sulfur carrier protein TusA family. | 0.936 |
| Bccel_1479 | Bccel_2229 | Bccel_1479 | Bccel_2229 | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | 6-deoxyerythronolide-B synthase, 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: Acyl transferase, Beta-ketoacyl synthase, KR domain protein, acyl carrier protein familyprotein; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | 0.999 |
| Bccel_1479 | Bccel_3070 | Bccel_1479 | Bccel_3070 | 6-deoxyerythronolide-B synthase; PFAM: KR domain protein, acyl carrier protein familyprotein, Beta-ketoacyl synthase, Acyl transferase; KEGG: polyketide synthase family protein; SMART: Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase/Fatty acid synthase, KR, Polyketide synthase, acyl transferase domain-containing protein. | PFAM: Uncharacterized protein family UPF0311; KEGG: cellulosome protein dockerin type I. | 0.809 |